Director, Supply Chain Network Planning, Cell & Gene Therapy

The Director Supply Chain Network Planning Cell & Gene Therapy will lead end-to-end planning strategy network design capacity management and supply orchestration across the Cell & Gene Therapy portfolio including Ex Vivo therapies such as CAR-T and gene-modified cell therapies as well as In Vivo gene therapies. This leader willbe responsible forbuilding and executing scalable planning processes that support patient access supply continuity launch readiness and long-term portfolio growth.

This role will oversee integrated planning across patient demand treatment center capacity apheresis scheduling manufacturing slot allocation viral vector supply drug substance drug product inventory distribution and external partner networks. The Director will partner closely with Commercial Clinical Operations Manufacturing Quality Regulatory Finance Technical Operations and external partners to ensure the network can reliably deliver therapies to patients while balancing service cost capacity compliance and business priorities.

As a senior leader this individual will develop planning capabilities mentor and grow future supply chain leaders and foster a culture of accountability operational excellence collaboration and continuous improvement. The role hasdirectimpact on product availability patient delivery supply resilience and overall business performance.

Key Responsibilities

• Lead integrated business planning across Commercial Clinical Operations Manufacturing Quality Regulatory Finance Technical Operations and external partner teams.

• Develop short- mid- and long-range demand supply inventory and capacity plans for commercial and clinical Cell & Gene Therapy products.

• Translate portfolio demand into manufacturing viral vector drug substance drug product inventory and distribution requirements.

• Drive scenario planning risk assessments and executive decision-making to support growth launch readiness and supply continuity.

• Ensure planning processes support uninterrupted supply reliable patient delivery and strong operational performance across the network.

Ex Vivo CAR-T Planning

• Own planning for individualized make-to-order CAR-T therapies across the end-to-end patient and manufacturing journey.

• Manage manufacturing slot allocation and capacity planning across internal and external manufacturing networks.

• Coordinate planning across apheresis scheduling manufacturing execution product release and treatment center delivery requirements.

• Optimizepatient flow and manufacturing throughput whilemaintainingChainof Identity and Chain of Custody requirements.

• Lead recovery planning for manufacturing failures patient delays supply disruptions and capacity constraints.

Viral Vector and In Vivo Planning

• Lead global viral vector demand and supply planning across commercial and clinical programs.

• Build integrated plans that connect plasmid supply vector manufacturing drug substance fill-finish and drug product operations.

• Establish inventory and deployment strategies for viral vectors drugsubstance and finished products.

• Align vector capacity and long-term portfolio demand to support commercial growth clinical development and launch readiness.

• Support commercialization planning for In Vivo gene therapy products.

Network Strategy Risk Management and Digital Planning

• Develop and execute the long-term supply chain network strategy for Cell & Gene Therapy products.

• Lead network assessments capacity analyses and supply chain design initiatives across internal manufacturing CDMOs warehousing cryogenic storage and distribution partners.

• Identifyand mitigate risks related to critical materials viral vector supply manufacturing capacitylogisticsproviders and external partners.

• Establish contingency plans and network resiliency strategies to reduce supply risk and support business continuity.

• Drive adoption of advanced planning tools KPI dashboards predictive analytics and scenario modeling to improve planning decisions and operational performance.

Team Leadership and Capability Building

• Lead coach and develop a high-performing team of supply chain planners analysts and managers.

• Set clear expectations build development plans andestablishsuccession strategies for the planning organization.

• Mentor emerging leaders and create growth opportunities across the team.

• Build organizational capabilities in end-to-end planning capacity management network design analytics and supply chain decision-making.

• Foster a culture of collaboration accountability innovation continuous improvement and patient-centric execution.

Basic Qualifications

• PhD and 8 years of progressive supply chain experience within biotechnology pharmaceuticals biologics or advanced therapies; OR

• Masters degree and 10 years of progressive supply chain experience within biotechnology pharmaceuticals biologics or advanced therapies; OR

• Bachelors degree and 12 years of progressive supply chain experience within biotechnology pharmaceuticals biologics or advanced therapies.

Preferred Qualifications

• MBA MS in Supply Chain Engineering Life Sciences ora relateddiscipline.

• 12 or more years of progressive supply chain experience within biotechnology pharmaceuticals biologics or advanced therapies.

• 7 or more years of leadership experience in planning supply chain strategy network planning operations ora relatedfunction.

• Experience supporting commercial CAR-T Cell Therapy Gene Therapy or Advanced Therapy Medicinal Products.

• Strong knowledge of vein-to-vein supply chains manufacturing slot management apheresis planning viral vector manufacturing cryogeniclogistics Chain of Identity and Chain of Custody requirements.

• Experience supporting complex regulated manufacturing environments.

• APICS/ASCM CPIM CSCP CLTD or equivalent certification.

• Demonstrated success leading teams through growth transformation operational scale-up product launches or business process improvement.

Technical Expertise

• Integrated Business Planning and S&OP leadership.

• Capacity planning capacity modeling and supply chain network design.

• Inventory optimization scenario planning and risk management.

• SAP IBP SAP S/4HANA Kinaxis Oracle SCM or equivalent planning platforms.

• Power BI Tableau SQL advanced analytics and KPI dashboard development.

Leadership Competencies

• Strategic thinking and strong business judgment.

• Patient-centric leadership and operational accountability.

• Executive presence and cross-functional influence.

• Peopledevelopment coaching and organization building.

• Change leadership financial acumen risk management and data-driven decision-making.

Success Profile

The successful candidate will build and lead an integrated scalable planning organization that enables reliable patient delivery strong supply continuity efficient manufacturingutilization and sustainable portfolio growth. This leader will be viewed as a trusted strategic partner a strong people leader and a driver of planning excellence across the Cell & Gene Therapy network.