Director, RDU IT Business Partner, Commercial Alexion

WHY JOIN US

At Alexion a division of AstraZeneca we are driven by a shared purpose to transform the lives of people affected by rare and devastating diseases. By combining deep expertise in rare disease with the scale science and innovation of AstraZeneca we are working to deliver meaningful advances for patients and families with significant unmet needs.

Join us at an exciting time as we continue to evolve how technology data digital capabilities and AI support our Commercial organization. You will have the opportunity to work closely with business and technology leaders shape solutions that enable new product launches and commercial transformation and help turn emerging technologies into measurable outcomes for patients and the business.

Our culture is built on collaboration innovation and continuous learning. We encourage our people to challenge convention explore new possibilities and bring forward ideas that can improve how we work and how we serve patients. As part of Alexion you will have the opportunity to make an impact in a highly specialized area of healthcare while benefiting from the capabilities and global reach of AstraZeneca.

Hybrid Policy
We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and meaningful in-person collaboration. This role is based in Boston MA with employees expected to work from the office three days per week creating opportunities for teams to connect collaborate and solve complex challenges together.

Introduction
As Director RDU IT Business Partner US Commercial you will serve as a senior business-facing technology partner shaping and delivering technology data digital and AI-enabled capabilities that support commercial priorities launch readiness commercial transformation and improved patient outcomes.

This position is based in Boston MA and may require up to 20% travel.

This role will build trusted relationships with senior Commercial stakeholders shape the multi-year technology and AI roadmap for assigned business areas lead demand prioritization steward portfolio health and partner across IT Digital Data AI Architecture Cybersecurity Privacy Compliance Finance Service Delivery and external partners to deliver measurable business outcomes.

• Serve as a senior IT Business Partner and trusted advisor for assigned US Commercial business areas aligning technology data digital and AI roadmaps to business priorities.

• Build and maintain trusted relationships with senior stakeholders across US Commercial Commercial Training Rare Disease Therapy Area teams launch Finance Commercial Operations Market Access and enabling functions.

• Partner with business leaders to translate strategic objectives into capability roadmaps prioritized demand investment options and measurable outcomes.

• Steward assigned Commercial IT portfolio activities including demand intake prioritization funding alignment risks dependencies value realization ServiceNow visibility and executive reporting.

• Lead disciplined business capability mapping and technology roadmap development ensuring roadmaps reflect business strategy process maturity data readiness AI opportunity and adoption needs.

• Support Market Access and GTN priorities at the portfolio level by translating key business needs into scalable compliant technology and data-enabled solutions.

• Ensure assigned commercial solutions include appropriate governance compliance privacy financial controls adoption planning and measurable value outcomes.

• Lead launch technology planning for new products indications and therapy area priorities with Sales Marketing Commercial Training Market Access and business operations.

• Lead through influence across business IT data AI architecture delivery and vendor teams; coach colleagues on business partnering AI literacy portfolio governance executive communication and value realization.

• Enable AI for the business by identifying framing prioritizing and scaling high-value AI GenAI agentic AI automation analytics and data product opportunities across US Commercial workflows.

• Translate AI ideas into business-ready use cases with clear problem statements target users data requirements operating model impacts success measures risks and adoption requirements.

• Drive AI-enabled business outcomes across commercial decision support launch readiness Commercial Training enablement executive reporting forecasting support customer engagement and portfolio prioritization.

• Champion responsible AI adoption by partnering with Data AI Architecture Cybersecurity Privacy Legal Compliance and business stakeholders to define explainability traceability human oversight auditability security and value measurement requirements.

• Move the business from AI experimentation to measurable business impact by defining baselines success metrics adoption targets governance requirements and continuous improvement loops.

• Model AI-enabled business partnering by using approved AI tools and LLM-enabled workflows to improve stakeholder preparation meeting synthesis portfolio reporting roadmap development risk identification executive communication and follow-through.

• Use AI-assisted analysis to improve demand intake synthesize stakeholder feedback compare requirements identify duplicate or overlapping requests and generate clearer business problem statements.

• Apply AI to organize knowledge transition documentation initiative history open risks dependencies decisions and stakeholder context while validating outputs and protecting sensitive information.

• Coach business and IT partners with practical compliant AI usage patterns that improve productivity quality decision speed and accountability.

• Bachelors degree in computer science MIS Business Life Sciences Data / Analytics or related fields.

• 12 years of experience in IT digital data commercial technology or enterprise technology roles including business partnership portfolio ownership solution delivery and cross-functional leadership.

• Experience working in biotech pharmaceutical medical device life sciences or another regulated industry.

• Demonstrated experience as a senior IT Business Partner or technology leader supporting Commercial Sales Marketing Market Access Patient Services Commercial Operations Finance or related business functions.

• Strong understanding of US Commercial business processes launch planning sales and marketing operations commercial operations portfolio governance and value realization.

• Working knowledge of Market Access GTN commercial operations and related financial decision-support processes.

• Experience shaping or delivering data analytics digital automation AI or technology-enabled transformation capabilities.

• Experience with CRM and related commercial platforms such as Salesforce Veeva or other life sciences commercial technologies.

• Strong understanding of data products analytics reporting commercial data foundations SDLC Agile practices privacy security quality compliance and regulatory expectations.

• Experience managing portfolio funding business cases risks dependencies vendor engagement and executive-level reporting.

• Ability to influence senior stakeholders simplify complexity drive alignment communicate technology concepts in business language and connect technology investments to business value patient impact efficiency adoption and risk reduction.

• Masters degree preferred.

• Experience supporting Commercial Finance Patient Services Launch Excellence Commercial Training Market Access or Rare Disease Therapy Area technology portfolios.

• Experience with Salesforce Health Cloud Salesforce Life Sciences Cloud Veeva Service Cloud Experience Cloud ServiceNow Snowflake data products BI / analytics platforms or AI-enabled commercial platforms.

• Experience with rare disease commercial models specialty pharmacy patient access payer engagement field reimbursement care coordination or high-touch business-facing environments.

• Experience leading governance forums executive portfolio reviews vendor partnerships product-oriented operating models transformation programs adoption plans and value-realization plans.

• Familiarity with responsible AI principles including explainability traceability human oversight auditability privacy compliance risk management and adoption of governance.

• Strong leadership presence with the ability to balance strategic thinking operational discipline stakeholder empathy and execution focus.

SO WHATS NEXT

To be considered for this exciting opportunity please complete the full application on our website at your earliest convenience it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit please share this posting with them.

Where can I find out more

• Explore what were building: connected and see our impact in action: today to shape the future of AI-powered rare disease care!
  Alexion is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. Alexion is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment assessment and selection process and may be requested by emailing.

  #LI-Hybrid
  
  The annual base pay for this position ranges from $153018.40 - $200836.65 pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and experience.

  In addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans.

  Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay(as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

  Date Posted

  25-Sept-2026

  Closing Date

  08-Oct-2026

  Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.