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Director, Assistant Controller

C4 Therapeutics


Job Location:

Watertown, NY - USA

Yearly Salary: USD 210520 - 232680
Posted: 21 October 2026 (2 days ago)
Application Deadline: 19 January 2027
Vacancies: 1 Vacancy

Job Summary

About C4 Therapeutics:

C4 Therapeutics (C4T) (Nasdaq: CCCC) is a clinical-stage biopharmaceutical company dedicated to delivering on the promise of targeted protein degradation science to create a new generation of medicines that transforms patients lives. C4T is progressing targeted oncology programs through clinical studies and leveraging its TORPEDO platform to efficiently design and optimize small-molecule medicines to address difficult-to-treat diseases. C4Ts degrader medicines are designed to harness the bodys natural protein recycling system to rapidly degrade disease-causing proteins offering the potential to overcome drug resistance drug undruggable targets and improve patient outcomes. For more information please visit .

Job Summary

C4 Therapeutics is seeking an experienced Assistant Controller to join our Accounting & Finance team at a pivotal moment in our growth. Reporting to the Controller this role will be a key technical and operational leader within Accounting with ownership over the close process internal controls and several of C4Ts most complex accounting areas including collaboration revenue clinical trial accruals and equity compensation. This is a highly visible role for an accountant who enjoys both the technical rigor of public company accounting and the opportunity to build and mentor a growing team. As C4T advances its pipeline into Phase 3 clinical trials and begins commercial readiness activities this individual will play an instrumental role in scaling the accounting function including building out the team implementing new systems and furthering our automation and AI integration efforts.


Your Role

  • Manage the monthly quarterly and annual close process ensuring accuracy timeliness and compliance with U.S. GAAP and public company reporting standards.
  • Review balance sheet account reconciliations and supporting schedules prepared by the accounting team ensuring completeness accuracy and timely resolution of open items.
  • Own collaboration revenue accounting including analysis of collaboration and license agreements under ASC 606 recognition of upfront milestone and royalty payments and related disclosures.
  • Oversee the Companys equity compensation program and stock-based compensation accounting including option RSU and ESPP activity ASC 718 accounting and common share/equity pool reconciliations.
  • Own and manage the Companys SOX internal control environment including control design execution documentation and remediation partnering with internal and external auditors as needed.
  • Play a key role in the preparation review and analysis of significant clinical trial accruals partnering closely with Clinical Operations and CRO vendors to ensure accurate estimates and timely reporting.
  • Serve as a mentor to and collaborate closely with other members of the Accounting team fostering technical development engagement and a strong team culture.
  • Work closely with the Controller and SVP Finance & Accounting on financial reporting forecasting and cross-functional initiatives that support the broader Finance organization.
  • Help build out the Accounting team as C4T advances into Phase 3 clinical trials and commercial readiness activities including participating in hiring onboarding and development of new team members.
  • Lead or support the implementation of new systems and process improvements furthering the teams automation and AI integration initiatives to increase efficiency and scalability.
  • Partner with external auditors on quarterly reviews and the annual audit including preparation of audit schedules and timely resolution of requests.
  • Research and document technical accounting matters and support the implementation of new accounting standards as applicable.
  • Perform other related duties and ad hoc projects as required by the position.


Your Background

Required:

  • A Bachelors Degree in Accounting with a minimum of eight years of progressive accounting experience including a combination of public accounting and life science industry experience with increasing levels of responsibility as well as an active CPA License.
  • Experience with revenue accounting including revenue recognition under U.S. GAAP (ASC 606).
  • Strong knowledge of U.S. GAAP SOX 404 internal control requirements and public company reporting standards.
  • A genuine passion for coaching mentoring and developing team members with a track record of building strong engaged teams.
  • Demonstrated ability to manage multiple priorities in a fast-paced dynamic environment with strong cross-functional partnering organizational and project management skills.

Preferred:

  • Advanced Degree in Accounting
  • Experience with commercial readiness activities or commercial-stage accounting (e.g. product revenue recognition gross-to-net accounting).
  • Experience with the implementation of accounting systems including ERPs and AI tools.


Compensation

The base pay range for this position at commencement of employment is expected to be between $210520.00 and $232680.00 annually; however base pay offered may vary depending on multiple individualized factors including job-related knowledge skills and experience.


C4 Therapeutics is an Equal Opportunity Employer.


Required Experience:

Director