Crystallization Scientist (Contract)

Job Summary

Vertex is seeking a talented individual to join ourEngineering and Materials Sciencesgroup in Boston MA on a temporary contract basis.

Engineering and Materials Sciencesat Vertex plays a vital role in bridging the gap between new pharmaceutical discoveries and commercial products. Engineers at Vertex work in multidisciplinary scientific teams to bring basic medical discoveries to patients and physicians by applying fundamental chemistry and chemical engineering principles to new products processes and development technologies.

The successful candidate will be a highly productive results-oriented individual able to generate and implement original ideas and solutions that contribute materially to the success and development of drug substance communication organization and planning skills anda high levelof technical aptitude and creativity arerequiredfor success in this position.

Job Description

The successful candidate willbe responsible for:

Supporting drug substance process development on a laboratory/bench scaleand in particular developinganddemonstratingearly fit-for-purpose API crystallizations leading to commerciallyviableAPI particle forming processes. These would include the development of crystallization isolation drying sizereductionand other particle engineering operations.

Basic and Preferred Qualifications include:

MS/BS degree with 2 - 5 years of pharmaceutical industry experience. Degrees with a life science concentrationrequired with a preference for concentrations in chemical engineering or chemistry.

Knowledge and experience in API process development and scale up in particular small molecule crystallization and particle engineering operations.

A demonstrated understanding and working knowledge of chemistry and chemical engineering fundamentals; applied kinetics thermodynamics and transport fundamentals; as well as familiarity with modern laboratory instrumentation (HPLC GC FTIR Raman FBRM DSC TGA XRPDetc) and common laboratory automation tools.

Experience with statistical design ofexperiments;QbDconcepts;and familiarity with common physical property and process modeling tools (AspenDynochemMatlab etc.).

The ability to successfully interact and collaborate within an interdisciplinary team environmentcomprisedof organic physical and analytical chemists project team members and manufacturing personnel.

Proven communication (verbal and written) and interpersonal skills.