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Computational Biology, Research Engineer Intern

Mantlebio


Job Location:

San Francisco, CA - USA

Monthly Salary: m 8500 - 10000
Posted: 29 September 2026 (3 days ago)
Application Deadline: 27 December 2026
Vacancies: 1 Vacancy

Job Summary

About MantleBio

At MantleBio our mission is to help people live longer healthier lives by advancing software for life science research.

Biotech generates a tremendous amount of data and is estimated to have the largest volume of data of any industry by 2025. Recent breakthroughs in computer science and machine learning have the opportunity to profoundly impact scientific research. However the majority of biotech companies lack the tools or software team necessary to fully utilize these advances and the data they have.

Our goal is to bridge the gap between biological data and cutting-edge technology by building modern data engineering software for the biotech industry.

MantleBio was founded in 2023 and is rapidly growing. The founding team has significant experience building large-scale data infrastructure for biotech from GRAIL ArsenalBio the Broad Institute and Google. MantleBio is backed by Y-Combinator has recently raised a seed round and has significant runway.

We are seeking a driven computational biologist who thrives in fast-paced environments to join our team.

About this Role

As an early member of the team and the first intern you will play a key role in the development of MantleBio:

  • Work closely with teammates to define and implement bioinformatics workflows on the Mantle platform

  • Collaborate with the product team to influence product direction

  • Opportunity to explore new applications for leveraging Mantles technology in biology research

  • Report directly to the CEO

About You

Requirements

  • 3 years of experience developing algorithms pipelines or software for life science research

  • Proficiency with the Python programming language

  • Experience in collaborative interdisciplinary work

    • Examples: working on a research project with multiple labs developing an open source library creating a bioinformatics pipeline for other members of your team designing your labs data management processes etc

  • Strong communication ability

    • Examples: Being a TA creating educational material or documentation teaching coworkers to use new tools or methods writing articles presenting research etc

Nice to Have

  • Experience working on bioinformatic data pipelines (e.g. Airflow Nextflow Snakemake)

  • Experience working in the biotech industry

  • Experience with software infrastructure tools: AWS Docker Relational Databases

  • Experience with analysis languages: R Shell scripting

  • Experience applying statistics or machine learning

Life at MantleBio

We work hard because we love what we do. As an early member of the team this is an opportunity to help define the culture of MantleBio.

We value ourselves in

  • Scientific Curiosity: We embed ourselves in the science and constantly ask how we can help make a difference

  • Engineering Ethics: We build fast but with quality. We understand the importance of data security and safety for our clients and strive to use the best technology to support them

  • Collaboration: We believe that the best progress happens when diverse groups work together on shared goals

  • Dedication: We are committed to providing the highest quality services and products forour partners

Perks and Logistics

Salary: 8.5k - 10k per month

  • We work 4 days a week in person in downtown SF to foster collaboration while allowing flexibility and heads down work time

  • Flexible start date: March 20 to May 20

  • Flexible duration: 8 weeks to 12 weeks

  • Unlimited PTO

  • Competitive health insurance and benefits

Even if you feel like you dont meet all of the qualifications we encourage you to apply!

Research shows that while men apply to jobs where they meet an average of 60% of the criteria women and other underrepresented people tend to only apply when they meet 100% of the MantleBio we welcome diverse perspectives and people who think rigorously and arent afraid to challenge the status quo. If youre interested in joining us then we encourage you to apply even if you dont perfectly match every single bullet on the job description.We promise to review your application. Mantle Bio is an equal opportunity employer and was founded by two women engineers. We celebrate diversity and are committed to creating an inclusive environment free from discrimination or harassment for all employees.

Interview Process

We believe that you should not need to study to prepare for an interview. Our interviews are light weight and focused on the true day to day work of this role.

Our interview processes consists of two virtual technical interviews and an optional onsite to meet the team.

If you have any questions please email . We are excited to hear from you.


Required Experience:

Intern