Biomarkers Research Lab Scientist (Ligand Binding Assays)

Job Description

Company Overview:

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Our teams bring together deep scientific expertise advanced technologies and a commitment to improving patient outcomes through discovery development and delivery of innovative therapies. Within Vertex the Biomarkers organization plays an important role in advancing clinical development through biomarker research assay development and cross-functional collaboration.

Role summary:

Vertex is seeking a hands-on Biomarkers Research Lab Scientist to develop and optimize biomarker assays that support clinical trials at Vertex. This individual will design and execute experiments to characterize novel biomarkers in human biofluids and tissues. This role offers the opportunity to contribute to innovative clinical biomarker studies while collaborating closely with members of the Biomarkers lab team and as needed with Research Quality and Biomarker Leads. The ideal candidate brings strong laboratory experience effective communication skills and a collaborative approach.

Key Duties & Responsibilities:

• Develop innovative biomarker assays for clinical studies at Vertex through hands-on laboratory work

• Characterize biomarkers in human biofluids and tissues and evaluate assay feasibility

• Perform mock validation experiments and contribute to the generation of data packages supporting assay readiness

• Partner with members of the biomarkers group to support assay transfer to CROs and external laboratories including technical handoff and troubleshooting

• Analyze interpret and present experimental results to internal stakeholders and project teams

Required Education and Qualifications:

• Ph.D. or equivalent degree with 03 years of relevant post-doctoral employment experience or

• Masters degree or equivalent degree with 3 years of relevant employment experience or

• Bachelors degree or equivalent degree with 6 years of relevant employment experience

• Hands-on experience developing ligand binding assays for translational or clinical applications

• Strong laboratory experience in molecular biology and cell biology

• Effective communication and interpersonal skills with proven ability to work effectively as a member of a multidisciplinary team

Technical Skills Required:

• Method development and validation experience in ligand binding assays including immunoassays and ELISA

• Biomarker assay development optimization and troubleshooting

• Western blot

• Protein labeling and quantification

• Molecular biology techniques

• Cell biology techniques

• Data interpretation and scientific presentation skills

Preferred Skills:

• Experience with cell culture and cell-based assays

• Experience with genomic assays such as qPCR ddPCR and NGS

• Experience with flow cytometry assays

Benefits:

• Opportunity to contribute to innovative biomarker research supporting clinical development

• Exposure to translational and clinical biomarker assay work within a collaborative environment

• Competitive compensation and comprehensive employee benefits

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at