Biology Research Scientist Remote

Job Type: Contractor
Location: Remote
Hours: 1020 hours/week
Duration: 12 months minimum with likely extension
Start: Immediate

We are seeking experienced Biology Research Scientists to support a project focused on validating protein target assignments against primary scientific sources and UniProt records.

You will review research papers and patents identify target assignment errors propose corrected UniProt accessions and provide concise evidence-based scientific reasoning.

• Review primary research papers and patents to verify protein target assignments.
• Compare target assignments against UniProt and identify discrepancies.
• Classify target assignment errors using a structured taxonomy.
• Propose accurate UniProt accessions where assignments are incorrect.
• Document clear concise evidence-grounded reasoning for each determination.
• Apply expertise in pharmacology biochemistry molecular biology or chemical biology to evaluate target relationships.

• Protein Target Identification
• UniProt
• Primary Literature Review
• Protein Biochemistry
• Molecular Biology
• Pharmacology
• Binding & Functional Assays
• Scientific Data Interpretation
• Evidence-Based Reasoning
• Technical Documentation

• BA/BS 5 years MS 2 years or PhD with relevant industry/drug discovery experience.
• Background in pharmacology biochemistry molecular biology or chemical biology within biotech pharma or CRO environments.
• Hands-on experience with assays such as SPR TR-FRET radioligand binding kinase assays or GPCR functional assays.
• Experience interpreting IC50 Ki and Kd data.
• Currently active in a bench-based research scientist or associate scientist role.
• Working knowledge of UniProt or related workflows such as SAR HTS target validation biochemical profiling or IND-enabling studies.

• Experience with ChEMBL BindingDB or PubChem.
• Selectivity profiling or counterscreening experience.
• Understanding of agonist/antagonist vs. activator/inhibitor distinctions.

1. What is your highest relevant degree and how many years of industry research experience do you have
2. What is your experience with protein target identification and UniProt
3. Which binding or functional assays have you performed hands-on
4. Do you have experience interpreting IC50 Ki or Kd data
5. Have you worked with ChEMBL BindingDB or PubChem
6. Are you currently bench-active in a research or scientist role
7. Are you available for 1020 hours per week with an immediate start