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Automation Engineer II
Job Location:
Job Location:
San Mateo, CA - USA
Yearly Salary:
USD 150000 - 168000
Yearly Salary:
Posted:
2 September 2026 (Yesterday)
Posted:
Application Deadline:
1 December 2026
Application Deadline:
Vacancies:
1 Vacancy
Vacancies:
Job Summary
The role: BigHat Biosciences is seeking a hands-on Automation Engineer to build support and sustain the automated workflows that power our high-throughput antibody production and characterization platform. We are looking for someone motivated by more than the engineering itself: they want their work to help bring cures to patients faster by leveraging an automated ML-driven antibody engineering platform.
This position reports directly to Keltoum Boukra and works in close collaboration with the Lab Automation team alongside scientific production and software partners across the platform.
*At BigHat we believe in titles that commensurate with skill set relative organizational impact and value contribution; more experienced candidates are encouraged to apply with the understanding that
responsibilities and title would adjust as appropriate.
Key Responsibilities
- Own automation projects end-to-end: lead the design build validation and deployment of new automated workflows from requirements through production release taking technical ownership of the result.
- Partner with scientific and production teams to scope projects translate assay needs into robust automated workflows and onboard them into routine use.
- Maintain and troubleshoot instruments and automated methods and support lab users to keep the platform running and operators unblocked.
- Document automation procedures and SOPs support knowledge transfer and contribute to the growth of the automation teams know-how.
- Collaborate with software engineering teams on end-to-end integrated workflows leveraging BigHats software stack.
Skills Knowledge and Expertise
- 3 years of relevant lab automation or liquid-handling industry experience.
- Hands-on experience in liquid-handler method development (e.g. Hamilton Venus Tecan FluentControl Beckman Biomek Agilent VWorks Analytik Jena Composer or similar) with Hamilton STAR or Vantage strongly preferred.
- Hands-on experience troubleshooting and maintaining liquid handlers and supporting automation users in the lab.
- Experience partnering with scientific and production teams to scope build and onboard automated workflows.
- Working knowledge of experimental design process documentation and data analysis.
- Strong communication skills with the ability to work across diverse teams (protein scientists research associates data scientists software engineers).
- A genuine drive to contribute and the curiosity to keep learning and take on unfamiliar problems adding to the team through fresh problem solving complementary expertise or new tools and practices.
- Experience automating high-throughput protein production and characterization workflows a strong plus though not required.
- Comfort working in a fluid dynamic start-up environment.
- Willingness to work onsite as the role is hands-on with instruments and in-lab support so physical presence is required.
Total Rewards
The salary estimated for this position is $150000 - $168000 bonus options benefits. Compensation will vary depending on job-related knowledge skills and experience. Actual compensation will be confirmed in writing at the time of the offer.
Required Experience:
IC
About Company
BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology. BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these desig ... View more
