Associate Scientist, Post Doc Fellow- Quantitative Pharmacology and Pharmacometrics

Job Description

Job Description

Be a part of the legacy: Postdoctoral Research Fellow Program

Our Research Laboratories Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers designed to provide you with an academic focus in a commercial environment. With the resources reach and expertise of a large pharmaceutical company postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview:

Scientific Question

Half-life extended or Fc-modified biologics offer important opportunities to improve the prevention and treatment of disease including in pediatric populations. Translating pharmacokinetic knowledge across populations remains scientifically challenging and requires fit-for-purpose quantitative approaches. The goal of the project is to advance translational pharmacokinetic modeling to support pediatric exposure prediction and dose selection using available nonclinical and clinical data. This project will focus on developing and applying quantitative modeling approaches to address key questions in pediatric drug development. The research will generate broadly applicable scientific insights strengthen model-informed decision-making and support the development of long-acting therapeutics.
Thats where you come in

What is the Position

As a Postdoctoral Research Fellow in Quantitative Pharmacology and Pharmacometrics you will work with a collaborative team of scientists in quantitative pharmacology preclinical ADME translational PK/PD and discovery biology. You will develop and apply quantitative pharmacology models to characterize pharmacokinetics support translation across populations and inform pediatric development. You will evaluate model assumptions and uncertainty integrate data from multiple sources and communicate findings to multidisciplinary research teams. All Postdoctoral Research Fellows work with a dedicated mentor collaborate with experienced scientists and are fully integrated into the larger Quantitative Pharmacology and Pharmacometrics group.

Responsibilities include but are not limited to:

• Reviewing and curating relevant nonclinical and clinical pharmacokinetic data from published and internal sources;

• Integrating data from multiple sources to support quantitative model development evaluation and application;

• Developing and qualifying fit-for-purpose pharmacokinetic and translational models to address questions in pediatric drug development;

• Evaluating model performance and uncertainty and translating results into recommendations for multidisciplinary project teams;

• Present your research at conferences and/or publish in peer-reviewed journals.

Education Requirement:

• Must currently hold a Ph.D. OR
• Receive a Ph.D. no later than spring 2027
• Ph.D. in mathematical biology systems biology statistics / biostatistics mathematics / applied mathematics computer science computational biology / chemistry pharmacokinetics and pharmacodynamics pharmacometrics chemical / biomedical engineering or a related field.

Required Experience and Skills:

• Experience with pharmacokinetic modeling (e.g. population PK popPK modeling physiologically-based pharmacokinetic PBPK modeling);
• Proficiency in at least one programming language or pharmacometrics application (e.g. R MATLAB Python NONMEM Monolix Phoenix WinNonlin or other language);
• Scientific writing skill demonstrated by publication record (includes preprints).

Preferred Experience and Skills:

• Knowledge of monoclonal antibody pharmacokinetic properties respiratory viruses pediatric pharmacology translational modeling or biologics drug development;

• Experiencing modeling preclinical or clinical pharmacokinetics of monoclonal antibodies;
• Experience working in multidisciplinary teams that include clinicians and biologists.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we follow the science that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

postdoctoralopportunities

The salary range for this role is: $82000-$92000

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days

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