Associate Director, Quantitative Pharmacology and Pharmacometrics, Cardiometabolic

Job Description

The Quantitative Pharmacology and Pharmacometrics (QP2) Department within our Companys Research Laboratories in Rahway NJ and West Point PA is excited to welcome a curious collaborative and scientifically driven Associate Director to help support our growing cardiometabolic pipelines.

In this role you will represent QP2 on cross-functional teams of experienced scientists working together to discover and advance novel therapeutic agents for cardiometabolic and ophthalmologic diseases. You will contribute to the discovery and development of small molecules biologics and non-traditional therapeutics including peptides novel biological constructs and other emerging modalities. The successful candidate will be a skilled quantitative drug developer with a strong integrated understanding of the strategic elements of drug discovery and development a collaborative mindset excellent communication skills and the ability to work independently with minimal supervision.

Within QP2 you will have a unique opportunity to grow your career as a quantitative drug developer while contributing to an end-to-end pipeline in one of the worlds most research-intensive biopharmaceutical companies. We offer a collaborative mission-driven environment where your scientific expertise can help shape meaningful decisions and advance innovative therapies for patients.

Responsibilities:

• • Develop and apply model-based strategies including translational PK/PD approaches mechanistic models population PK/PD analyses and clinical trial simulations to inform quantitative decision-making within and across development programs and departments. These efforts will help optimize drug discovery and development decisions including dose selection clinical trial design and go/no-go recommendations.

  • Represent QP2 on cardiometabolic discovery early clinical development and late clinical development teams using quantitative approaches to support efficient evidence-based advancement of programs across these growing portfolios.

  • Partner collaboratively with functional area colleagues external vendors and strategic partners to build aligned quantitative and model-informed approaches that support drug discovery development and regulatory decision-making.

  • Collaborate across disciplines on study design protocol development study execution data interpretation reporting and communication of results.

  • Maintain a strong understanding of global regulatory expectations and contribute to the development presentation and defense of regulatory documents and submissions.

  • Work closely with pharmacometrics colleagues to provide scientific input on modeling strategies analyses interpretation and reporting.

Required:

• • Ph.D. or equivalent degree with at least 4 years of relevant experience; PharmD or equivalent degree with at least 6 years of relevant experience; or MS or equivalent degree with at least 8 years of relevant experience. Relevant experience should reflect increasing responsibility and independence in pharmaceutical drug development a regulatory agency or academia.

  • Educational background in biopharmaceutics pharmaceutical sciences pharmacometrics chemical or biomedical engineering or a related quantitative discipline.

  • Experience conducting population PK and PK/PD analyses using standard pharmacometrics software such as R Matlab Phoenix NONMEM Monolix or similar tools.

  • Strong written and verbal communication skills with demonstrated ability to collaborate across disciplines scope complex problems and plan work effectively.

  • Knowledge in modeling complex therapeutics mechanistic modeling/ QSP.

Preferred:

• • Knowledge of cardiometabolic clinical drug development programs.

  • Advanced skills in mathematical problem-solving critical data analysis and interpretation experimental design and statistics.

  • Scientific understanding of the biopharmaceutical and ADME properties of small molecules and/or biologics.

  • A strong record of increasing responsibility independence and demonstrated impact in advancing drug development decisions through model-based approaches.

Required Skills:

Preferred Skills:

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The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

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