Senior Technical Manager (External Manufacturing)

We are now looking for a Technical Specialist to join our Global Supply Chain (GSC) Digital and Technology function to provide global technology leadership for shaping and delivering digital integration Smart Manufacturing and AI-enabled transformation across GSKs External Manufacturing and partner network.

Job Purpose:

The Senior Tech Manager (External Manufacturing) acts as the business-technology integrator between GSKs departments and Contract Development and Manufacturing Organization (CDMO) partners. The GSK departments includes External Manufacturing Chemistry Manufacturing & Control (CMC) / New Product Introduction (NPI) Manufacturing Science & Technology (MSAT) Quality Supply Chain R&D and global Digital and Technology product teams. The role translates operational and technology priorities into integrated roadmaps and scalable solutions across enterprise platforms.

The role is explicitly global (rather than aligned to a specific site) but will utilise site insight to validate value and feasibility then standardises integration patterns data models AI-use cases and deployment approaches for re-use across products sites and external partners. The role leads end-to-end outcomes from opportunity shaping and business case through design delivery adoption transition to service and value realisation.

Key Responsibilities(include..):

• Lead the global External Manufacturing digital & technology roadmap aligning CMC/NPI technology-transfer manufacturing supply quality and partner priorities with enterprise Digital & Technology strategy (including Smart Manufacturing and AI-roadmaps).
• Own end-to-end delivery of digital integration solutions for External Manufacturing across enterprise technology environments. This extends to partnering directly with the External Manufacturing operations and selected CDMOs to identify operational challenges and rapidly shape prototype and validate high-value Smart Manufacturing data and AI-use cases (with clear evidence-based continue adapt or stop recommendations).
• Build internal & external collaboration with Tech vendors external companies & other industry bodies in addition to collaborating with GSK functions in order to stay current with latest Tech & industry trends.
• Lead product and programme delivery using Agile and hybrid methods including roadmap and backlog prioritisation user stories sprint and release planning Risks Assumptions Issues and Dependencies (RAID) management governance operational readiness adoption and measurable value realisation. Set release quality service level and support transition criteria for what ships and confirm they are met before handover.
• Ensure solutions are scalable beyond the target CMO by converting local learning into global product requirements reusable agents integration patterns reference architectures onboarding models and deployment playbooks for the wider External Manufacturing network.
• Act as the primary digital & technology partner across External Manufacturing site leadership and global product teams influencing distributed teams and external partners without direct authority. Embed Responsible AI cybersecurity privacy data governance GxP validation architecture service management and regulatory requirements from solution inception through industrialisation and lifecycle support.
• Manage your team in using approved AI tools for analysis prototyping and documentation to improve productivity role-modelling responsible use with human review and following GSKs Responsible AI privacy and security requirements.
• Develop investment cases and scaling strategies manage financial forecasts and supplier inputs and provide executive-level reporting on scope dependencies risks decisions benefits and return on investment.
• Build sustainable capability through coaching documentation knowledge transfer and communities of practice while ensuring validated solutions transition to accountable product or service teams for scale support and lifecycle ownership.

Location: The successful applicant can be based at GSK HQ (London) or at the Ware (Hertfordshire) or Barnard Castle (County Durham) manufacturing sites.

About You:

This role would suit ahighlymotivatedpersonwho hasstrong experienceofdesigning developing and validating AI-enabled digital solutions and Smart Manufacturing capabilities within complex manufacturing and business will have strong technical knowledge obtained from working in a highly-regulated demonstrablystrong people skills be resilient and calm under pressure have a strong continuous improvement mindset and a proven ability to drive performancewhile managing multiple stakeholders.

CLOSING DATE for applications:Monday 16th of November 2026 (COB).

Basic Qualifications:

• Relevant Degree (eg; Computer Science Software Engineering Data Science Artificial Intelligence Engineering Information Technology Manufacturing Systems or related technical discipline).
• Proven experience leading digital integration or technology transformation in manufacturing or supply-chain environments (External Manufacturing/ Contract Development and Manufacturing Organization (CDMO) experience preferred).
• Strong understanding / experience of CMC/NPI Supply Chain manufacturing and quality management systems (QMS).
• Demonstrated knowledge of integration architecture APIs middleware event/data platforms canonical data models and scalable factory integration layers (familiarity with Product Development & Lifecycle Management (PDLM) and FIL (Factory Integration Layer) is desirable).
• Experience shaping and delivering Smart Manufacturing AI agent-based data and analytics use cases including Proof of Concept (PoC) Proof of Value (PoV) Minimum Viable Product (MVP) and production scale-up.

We welcome people who bring curiosity humility and a practical approach. We are committed to inclusion and to creating a supportive environment where everyone can grow. If you enjoy solving real problems delivering measurable results and helping teams succeed we encourage you to apply. If you would like to learn more about our company wide benefits and life at GSK we would suggest looking at our webpageLife at GSK GSK.

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Why GSK

Uniting science technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade as a successful growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale.

People and patients around the world count on the medicines and vaccines we make so were committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients accountable for impact and doing the right thing is the foundation for how together we deliver for patients shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race color religion sex (including pregnancy gender identity and sexual orientation) parental status national origin age disability genetic information (including family medical history) military service or any basis prohibited under federal state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you we encourage you to explore with our hiring team what the opportunities are.

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