Senior Scientist Translational Developability

We are currently seeking an enthusiastic dynamic and self-motivated senior scientist to join the Translational Developability group within MDE and working within a matrix role. The role will be primarily lab focused working with teams of scientists with diverse skills including protein biochemists in vitro and ex vivo assay scientists antibody pharmacologists and molecular biologists as well as in close partnership with other parts of the GSK organisation. It involves using high throughput methods to rapidly profile large panels of antibodies and perform interpretations on the generated data in the early discovery phase. These activities will focus on in vitro prediction of antibody characteristics during exposure in vivo.

Large Molecule Research within GSK is a department dedicated to the discovery of novel and effective biopharmaceutical medicines. This department comprises several complementary functions focused on the progression of a portfolio of biopharmaceuticals from initial antibody discovery expression and characterisation to molecular engineering and biological and physiochemical profiling. Within the Large Molecule Discovery Unit the Molecular Design and Engineering (MDE) group takes accountability for antibody engineering and developability profiling prior to candidate selection to continuously improve molecule quality and transform discovered leads into potential therapeutics.

As a Senior Scientist you will lead laboratory science to characterise and de-risk therapeutic antibody and biopharmaceutical candidates. You will work closely with colleagues in discovery and early development to design and run experiments that deliver clear decision-making data.

This role offers hands-on laboratory work scientific ownership and opportunities to develop both technical and leadership capabilities while contributing to the progression of innovative therapies.

We create a place where people can grow be their best be safe and feel welcome valued and included. We offer a competitive salary an annual bonus based on company performance healthcare and wellbeing programmes pension plan membership and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK GSK

In this role you will

• Design and deliver experiments to characterise antibody-based molecules using a range of techniques such as chromatography-based analytical techniques such as SEC-HPLC and CIEX-HPLC as well as ELISA and flow-based assays.
• Analyse and interpret experimental data to provide clear actionable recommendations to project teams.
• Collaborate within multidisciplinary teams to support programme progression and scientific decision making.
• Maintain accurate experimental records and produce high-quality documentation including formal reports.
• Contribute to assay development qualification and optimisation to improve throughput and data quality.
• Promote safe laboratory practices and support equipment and reagent management.

Why you

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• Advanced degree (PhD or MSc with relevant laboratory expertise) in biochemistry biophysics pharmacology or related life science discipline or BSc with equivalent experience.

• Independence and competence performing relevant analytical/ biological research techniques (in one or more of the following: immunoassay flow cytometry SEC- HPLC );
• Pharmaceutical Biotech or CRO industry experience working on large molecules and knowledge of antibody structure and function;
• Experience of working with human biological materials such as serum or plasma

• Strong data analysis and interpretation skills with high attention to detail.
• Strong communication skills to present scientific findings to diverse audiences.

Preferred Qualifications & Skills:

Please note the following skills are not necessary just preferred if you do not have them please still apply:

• Exposure to large or complex datasets and data visualisation tools.

• Good understanding of antibody clearance mechanisms and related concepts

• Background in assay development qualification or automation.
• Familiarity with cell-based assays or molecular biology techniques.

• Experience of the use and design of automated solutions to scientific workflows including liquid handlers;

• Interest or experience in data science or statistical approaches to experimental design.

Location: For candidates seeking to be located at our Stevenage site this role will temporarily be based at Stevenage. However the Company plans to relocate its offices to Cambridge UK. The location of this role will therefore subsequently change to Cambridge UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.

Closing Date for Applications 6th October 2026 (COB)

Please take a copy of the Job Description as this will not be available post closure of the advert.

When applying for this role please use the cover letter of the online application or your CV to describe how you meet the competencies for this role as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

At GSK we have bold ambitions for patients aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines combining our understanding of the immune system with cutting-edge technology to transform peoples fosters a culture ambitious for patients accountable for impact and committed to doing the right thing making sure that we focus our efforts on accelerating significant assets that meet patients needs and have the highest probability of success. Were uniting science technology and talent to get ahead of disease together.

Find out more:

Our approach to R&D.

Skills

Why GSK

Uniting science technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade as a successful growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale.

People and patients around the world count on the medicines and vaccines we make so were committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients accountable for impact and doing the right thing is the foundation for how together we deliver for patients shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race color religion sex (including pregnancy gender identity and sexual orientation) parental status national origin age disability genetic information (including family medical history) military service or any basis prohibited under federal state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at where you can also request a call.

Please note should your enquiry not relate to adjustments we will not be able to support you through these channels. However we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

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