Principal Computational Methodologist (UK)

Make your mark for patients

We are looking for a Principal Computational Methodologist who is curious collaborative and impact-driven to join our Advanced Methods and Data Science team within Biometrics and Data Science based in any of our Brussels (Belgium) Slough (UK) or Raleigh (US).

About the role

You will help shape how advanced AI machine learning and computational methods support clinical development. You will design validate and deploy models that help teams make evidence-based decisions in areas such as biomarker discovery clinical trial design operational efficiency and patient experience. You will guide scientific thinking turn complex methods into practical solutions and help build scalable tools that meet scientific technical and regulatory expectations.

Who you will work with

You will join Advanced Methods and Data Science part of Biometrics and Data Science within Patient Evidence. You will work with clinical statistical molecular operational engineering IT governance and compliance colleagues across countries. You will also connect with academic technology and industry partners. Together you will explore new methods share scientific learning and support teams that use data to improve decision-making across the drug development value chain.

What you will do

• You will lead AI and machine learning projects that address clinical development biomarker operational and decision-support needs.
• You will design build test and refine modern deep learning models for text graphs biological sequences and clinical data.
• You will develop generative AI applications using foundation models pre-trained models and large language models.
• You will run rigorous reproducible AI experiments on internal and public datasets to generate publishable scientific results.
• You will partner with engineering teams to package methods into applications platforms and scalable validated solutions.
• You will mentor colleagues share knowledge and represent the team through publications presentations and external collaborations.

Interested For this role we are looking for the following education experience and skills:

• You have a PhD in Statistics Computer Science Engineering Computational Biology Statistical Genetics Mathematics or a related scientific field.
• You bring experience in industry ideally within pharma clinical development life sciences or another regulated data-focused environment.
• You can program confidently in Python R or similar languages and you can support others with practical coding guidance.
• You understand supervised unsupervised Bayesian and deep learning methods and can apply them to real-world scientific questions.
• You have experience with ML infrastructure reproducible research Linux or HPC environments and software or platform development.
• You communicate clearly with scientific technical medical and business partners and enjoy working in a collaborative multidisciplinary team.

Are you ready to go beyond to create value and make your mark for patients If this sounds like you then we would love to hear from you!

About us
UCB is a global biopharmaceutical company focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe inspired by patients and driven by science.

Why work with us
At UCB we dont just complete tasks we create value. We arent afraid to push forward collaborate and innovate to make our mark for patients. We have a caring supportive culture where everyone feels included respected and has equal opportunities to do their best work. We go beyond to create value for our patients and always with a human focus whether thats on our patients our employees or our planet. Working for us you will discover a place where you can grow and have the freedom to carve your own career path to achieve your full potential.

At UCB weve embraced a hybrid-first approach to work bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.