Clinical Scientist, Contractor

About Aura Biosciences

Aura Biosciences is a clinical-stage biotechnology company developing bel-sar a potentially transformative first-in-class therapy for patients living with ocular cancers. Bel-sar represents an entirely novel approach to treating ocular cancers via its dual mechanisms of action of acute tumor necrosis and secondary anti-tumor immune activation. The Phase 3 registration study of Bel-sar in early choroidal melanoma the largest patient segment of uveal melanoma is fully enrolled and earlier stage studies in metastases to the choroid and cancers of the ocular surface are ongoing. Auras mission is to improve outcomes for patients living with ocular cancers by delivering a therapy that not only arrests tumor growth but also preserves vision and quality of life.

For more information visit. Follow us on X @AuraBiosciences and visit us on LinkedIn.

Position Summary

Aura Biosciences is seeking a highly motivated Clinical Scientist Contractor to join our Clinical Development organization.

The Clinical Scientist will be a key scientific member of cross-functional study teams contributing to the design execution analysis interpretation and communication of Auras clinical programs. Working closely with the Vice President Clinical Development and colleagues across Medical Clinical Operations Biostatistics Safety Data Management Regulatory and other functions this individual will help translate clinical strategy into high-quality studies and actionable scientific evidence.

The successful candidate will combine strong scientific and clinical judgment with a hands-on approach to clinical data study execution and cross-functional problem solving.

Key Responsibilities

Clinical Data Review and Study Execution

• Conduct ongoing review and interpretation of clinical trial data including safety efficacy study conduct and data quality.
• Identify emerging clinical trends inconsistencies and data issues and work cross-functionally and proactively to drive timely resolution.
• Partner with Biostatistics and Data Management on data review plans patient profiles listings tables figures data cleaning and database lock activities.
• Serve as a clinical-science resource for study teams and partner with Clinical Operations to support high-quality study execution.

Clinical Development and Regulatory

• Contribute clinical and scientific input to clinical development plans study design and analysis approaches.
• Author and/or contribute to protocols and amendments clinical study reports investigator brochures regulatory briefing documents health authority responses and other key clinical documents.
• Evaluate emerging clinical data scientific literature and competitive programs to inform study and development strategy.
• Ensure clinical data and scientific rationale are presented clearly accurately and consistently across clinical and regulatory deliverables.

Scientific Communication

• Develop clear presentations of clinical data for study teams internal governance and external scientific audiences.
• Contribute to abstracts posters presentations manuscripts and other scientific communications.
• Maintain current knowledge of ocular oncology ophthalmology oncology drug development and the evolving therapeutic landscape relevant to Auras programs.

Cross-Functional Collaboration

• Collaborate effectively across Clinical Development Clinical Operations Biostatistics Data Management Safety Regulatory Affairs and other functions.
• Communicate clinical insights risks and recommendations clearly and bring a patient-focused evidence-based perspective to decision-making.
• Help develop fit-for-purpose clinical-science processes and ways of working appropriate for a growing biotechnology company.
• Demonstrate scientific rigor accountability flexibility and a willingness to work across traditional functional boundaries.

Qualifications

• Advanced degree in a relevant scientific or health-related discipline (PhD PharmD OD or equivalent) strongly preferred; candidates with an MS MPH or other relevant advanced degree and substantial clinical development experience may also be considered.
• 3 years of relevant experience in clinical research or drug development within biotechnology pharmaceuticals or medical devices.
• Experience supporting the conduct analysis and reporting of interventional clinical trials.
• Demonstrated ability to review and interpret clinical and scientific data and translate findings into clear conclusions and recommendations.
• Strong understanding of clinical trial methodology GCP and relevant regulatory requirements.
• Strong scientific writing presentation communication and cross-functional collaboration skills.
• Ability to take ownership manage multiple priorities and deliver high-quality work in a fast-paced evolving environment.

Preferred Experience

• Experience in ophthalmology oncology or rare disease drug development.
• Experience with Phase 2 and/or Phase 3 clinical development.
• Hands-on experience with efficacy and safety data review including patient profiles listings tables and figures.
• Experience contributing to regulatory submissions or interactions with health authorities is a plus.

Travel

Ability to travel domestically and internationally as required for study activities and other business needs. Expected travel approximately 1020%.

Contract Expecations:

Remote role in UK (not limited to London posting location)

Must be physically located in UK

Full time weekly hours (40 hours per week)

Expectations for year-long contractor (possibility for both/either extention/conversion depending on business need)

Must be authorized to work legally in UK

Required Experience:

Senior Manager