Associate Director, Portfolio Project Management

At Bicycle we benefit from a hybrid style working arrangement allowing employees where possible the opportunity to collaborate and engage with their coworkers in person while also benefiting from the flexibility of remote working. A typical hybrid arrangement for this role is 3 days onsite per week at our Cambridge UK office with the remainder of your working week remote.

Your mission is to serve as the operational engine of our cross-functional pipeline seamlessly bridging Research & Innovation (R&I) and Clinical Development. Working under the guidance of the VP Portfolio Strategy & Scientific Affairs and our Director-level project management leadership you will oversee the day-to-day coordination tracking and operational management of our therapeutic portfolio. By maintaining highly accurate integrated Gantt charts orchestrating clear meeting agendas capturing precise action-oriented minutes and tracking project interdependencies across departments you will enable our scientific and clinical teams to execute seamlessly mitigate risks and deliver the next wave of novel Bicycle therapeutics on time and within budget.

Portfolio Tracking Planning & Operational Excellence

• Master Timeline & Gantt Chart Management: Create maintain and continuously optimize integrated master project plans and detailed Gantt charts across both Research & Innovation (R&I) and Clinical programs identifying critical paths and key interdependencies.
• Meeting Administration & Governance Support: Coordinate and administer project team meetings. This includes driving the preparation of collaborative objective-focused agendas capturing high-quality action-oriented minutes and systematically tracking follow-up deliverables to closure.
• Portfolio Dashboards & Reporting: Maintain portfolio-level tracking tools dashboards and risk registries under the guidance of Director leadership to provide senior stakeholders with high-visibility real-time access to program statuses.
• Documentation & Repository Stewardship: Ensure all project-related documentation decision logs and collaboration portals (e.g. SharePoint MS Teams) are meticulously organized up-to-date and standardized across R&I and Clinical teams.
• Publications Support: Support publications tracking timelines and maintaining a publications repository across R&I and Clinical.

Pipeline Delivery & Operational Execution

• Cross-Functional Execution: Collaborate with team members across nonclinical translational clinical regulatory and CMC functions to ensure that project objectives and milestones leading to IND/CTA filings and clinical trial milestones are executed within scope and budget.
• Resource & Timeline Optimization: Proactively identify timeline variances operational inefficiencies and resource bottlenecks escalating them with constructive mitigation recommendations to project leaders and Director-level sponsors.
• Risk Tracking & Mitigation: Facilitate risk identification workshops/discussions at the project team level capturing risks within the project risk register and tracking the execution of agreed-upon mitigation plans.

Stakeholder Engagement & Business Partnership

• Operational Business Partnering: Act as a reliable operational partner to R&I and Clinical Project Leaders helping to translate complex scientific and clinical strategies into tangible trackable plans.
• Functional Alignment & Communication: Foster clear proactive and transparent communication across functions bridging communication gaps and ensuring that interdependencies are visible and managed.
• External Partner Coordination: Assist in managing PM activities for alliance partnerships CROs and external scientific collaborations ensuring meeting agendas minutes and deliverables are aligned with contract milestones.

Qualifications :

nowledge

• Core Expertise: You bring substantial experience and recognised domain expertise in portfolio and project management. You lead complex project planning initiatives advance our project management methodologies and understand how the PM function contributes to overall organisational performance.
• Data / Insight: You apply broad knowledge of project management principles to analyse often incomplete or evolving project information developing insights that influence strategic direction and timelines for our therapeutic portfolio.
• Influence & Collaboration: You act as a strategic contributor and mentor on project management best practices. You build and maintain cross-functional networks to coordinate complex program initiatives and influence decisions in high-impact situations such as scenario planning or risk mitigation.

Job Complexity

• Task / Project Delivery: You lead complex project management initiatives that span multiple teams with broader functional impact. You define clear approaches to address less-structured problems like timeline variances or resource constraints and ensure high-quality delivery of project plans and dashboards.
• Problem-Solving: You address complex and sometimes ambiguous portfolio challenges that affect cross-disciplinary work. You develop and refine project management policies methods and tools to support departmental and cross-functional objectives.
• Strategic Impact: You lead major project planning and tracking efforts with impact across multiple departments. You align project execution with functional priorities and drive the effective delivery of our pipeline programs.

Independence

• Autonomy: You operate with substantial autonomy in determining objectives and approaches for new or complex assignments such as building a project plan for a first-in-class asset. You exercise independent judgment in both technical PM matters and operational execution.
• Decision-Making: You make high-impact decisions affecting complex project initiatives and departmental performance. You exercise judgment within broad guidelines and are accountable for the accuracy and integrity of project timelines and data.
• Leadership / Mentorship: You lead cross-functional project teams providing direction on complex planning issues and developing the teams capability to navigate interdependencies.

Values & Behaviours

• One Team (Collaboration): You excel at building alignment across teams and departments ensuring seamless coordination between functions like R&I Clinical and CMC to achieve shared portfolio goals.
• Adventurous (Innovation): You drive the adoption of innovative project management practices such as new software tools or reporting methods that have a long-term impact on the efficiency and visibility of our portfolio.
• Dedicated to our Mission (Accountability): You ensure that project management outcomes such as on-time milestone delivery and proactive risk mitigation directly support our organisational mission to deliver novel therapeutics to patients.
• Resilience: You model perseverance and adaptability under pressure calmly navigating the complexities and challenges inherent in drug development timelines.

Qualifications

• Biopharmaceutical Project Management Expertise: Demonstrated significant experience in project management within the biopharmaceutical industry with a solid operational understanding of both discovery research (through to IND/CTA filing) and clinical development processes.
• Portfolio & Scheduling Proficiency: A proven track record of managing project schedules critical paths and cross-functional interdependencies across multiple overlapping therapeutic programs.
• Advanced PM Toolset Mastery: Exceptional hands-on expertise in project management software (e.g. MS Project Smartsheet) to build manage and present complex timelines and dashboards.
• Rigorous Meeting Facilitation & Administration: Outstanding organizational skills with a demonstrated ability to construct focused meeting agendas facilitate technical cross-functional discussions and capture clear action-oriented minutes.
• Adaptive Stakeholder Communication: Demonstrated ability to navigate ambiguous situations and communicate effectively with stakeholders at all levels translating complex program data into actionable project updates.
• Project Management Credentials: Formal project management training or certifications (e.g. PMP PRINCE2) are highly desirable but not essential where equivalent practical competency has been demonstrated.

Additional Information :

• Pension (10% employer contribution)
• Private Medical Insurance (PMI) (including optical and dental cover)
• Health Cash Plan
• Group Life Assurance (4x basic salary)
• Group Income Protection
• Employee Assistance Program (EAP)
• Cycle to Work scheme
• Access to subsidised gym membership
• Time off (28 days annual leave in addition to bank holidays & the option to buy up to 5 additional days annually)
• Competitive reward including annual company bonus
• Employee recognition schemes
• Enhanced parental leave policies
• Flexible working environment
• State-of-the-art campus environment with on campus restaurant and Montessori nursery
• Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore all qualified applicants will be considered for employment and we do not discriminate on the basis of race religion colour gender (including gender reassignment) sexual orientation age disability status marital status or veteran status. 

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore all qualified applicants will be considered for employment and we do not discriminate on the basis of race religion colour gender sexual orientation age disability status marital status or veteran status.

Remote Work :

No

Employment Type :

Full-time