ACE Portfolio medical strategy lead

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Job Description

The ACE Regional Portfolio Strategy Lead owns and drives the integrated cross-asset portfolio strategy across the ACE region ensuring consistent translation of global strategy into actionable regionally relevant execution guidance.

This role acts as the critical strategic bridge between Global and Country teams enabling aligned scientific positioning coordinated execution and proactive portfolio management across affiliates in a complex and heterogeneous environment.

Key Responsibilities

1. Regional Portfolio Strategy Leadership

• Own the ACE-level portfolio strategyacross all assets and disease areas.

• Translate global strategy into clear prioritised and actionable regional guidanceto support consistent country execution (e.g. POA alignment).

• Ensure coherent portfolio-wide scientific positioningacross the region.

2. Strategic Integration & Execution Alignment

• Drive alignment across Medical Affairs Government Affairs Public Affairs and other cross-functional stakeholders.

• Partner with ACE networks (e.g. CMD TA Leads GMA Execution Lead) to ensure consistent and high-quality regional execution.

• Enable best-practice sharing and adoption across affiliatesto reduce variability in execution.

3. Above-Country Scientific & External Engagement

• Own above-country relationships and engagement strategywith:

  • Payers Access and Government Stakeholders (PAGS)

  • Guideline committees

  • Professional associations

  • Independent Medical Education (IME) providers

• Provide regional medical leadership and input into:

  • Public Affairs / Government Affairs / GV&A strategy

  • EMA label strategy and timing

4. Portfolio Insights & Decision Support

• Deliver portfolio-level insights analysis and recommendationsto regional leadership.

• Identify and monitor emerging regional risks opportunities and external trends.

• Support proactive data-driven regional decision-makingin an increasingly complex portfolio.

5. Cross-Country Coordination & Issue Management

• Drive coordinated region-wide responses to scientific and strategic challengesaffecting multiple affiliates.

• Ensure early identification and mitigation of cross-country risks.

• Improve speed and quality of decision-making by reducing fragmentation and reactive approaches.

Scope & Impact

• Geography:ACE region (multi-country heterogeneous access and policy landscape)

• Portfolio:All assets across disease areas

• Level:Enterprise/Regional (ED or SD level)

Impact:

• Drives consistency in scientific messaging and executionacross affiliates

• Enhances strategic clarity and prioritisation at country level

• Strengthens external influence and stakeholder alignment

• Enables faster proactive portfolio decision-making

Key Interfaces

Internal

• Global Medical Affairs

• ACE Medical Leadership (CMD TA Leads affiliates)

• Government Affairs / Public Affairs / GV&A

• Commercial and cross-functional regional teams

• GMA Execution Lead

External

• Payers and policy stakeholders

• PAGS

• Guideline committees

• Professional associations

• IME providers

Critical Capabilities & Experience

Technical / Functional

• Deep understanding of portfolio strategy and lifecycle management

• Strong expertise in Medical Affairs and scientific positioning

• Experience with EMA label processes and regional policy environments

Leadership & Strategic Skills

• Ability to operate at enterprise/portfolio level rather than single-asset focus

• Strong strategic translation skills(global regional country)

• Proven capability in cross-functional and matrix leadership

• Skilled in navigating complexity and heterogeneity across markets

External Engagement

• Experience engaging with above-country stakeholders and influencers

• Strong understanding of health policy access and guideline ecosystems

Success Measures (Typical for Gilead Role Profiles)

• Alignment and consistency of portfolio execution across ACE affiliates

• Quality and impact of regional strategic guidance (POA alignment)

• Effectiveness of cross-country risk identification and mitigation

• Strength of external stakeholder engagement and influence

• Contribution to regional leadership decision-making and outcomes

Why This Role is Critical

This role addresses a structural gap between global strategy and country execution ensuring the ACE region can manage increasing portfolio complexitywhile maintaining consistency speed and strategic coherence.

Without it execution remains fragmented decision-making reactive and opportunities for regional scale and influence underleveraged.

The role is based in UK UK contract. We are pleased to share that Gileads Stockley Park and Holborn offices are planning to come together at a new London headquarters at 1 Triton Square NW1 from approximately Q2 2027. Applicants should consider this planned location change when applying for this role. Gilead operates a flexible working policy offering a balanced approach with two days of remote working and three days working onsite.

It is the policy of Gilead Sciences Inc. and its subsidiaries and affiliates (collectively Gilead or the Company) to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law all employment actions relating to issues such as compensation benefits transfers layoffs returns from layoffs company-sponsored training education assistance social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds which may include an individuals gender race color national origin ancestry religion creed physical or mental disability marital status sexual orientation medical condition veteran status and age unless such protection is prohibited by federal state municipal provincial local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.

Please apply via the Internal Career Opportunities portal in Workday.