Postdoctoral Scientist Ocaas Lab

Position Overview and Responsibilities
The Ocaas Lab at the Oklahoma Medical Research Foundation is seeking a motivated postdoctoral researcher interested in womens health ovarian biology brain aging neurodegeneration inflammation and/or single-cell and multi-omic approaches to aging biology.

Our lab studies how aging and sex-specific biology shape inflammatory and degenerative processes across tissues with a particular focus on the ovary and brain. Current projects investigate mechanisms of ovarian aging immune cell remodeling neuroinflammation microglial biology Alzheimers disease and the molecular links between reproductive aging and brain health. We use mouse models single-cell transcriptomics epigenomics spatial and molecular biology approaches and computational analyses to understand how aging-associated inflammatory pathways contribute to tissue dysfunction and disease.

The postdoctoral scientist will lead independent and collaborative projects focused on mechanisms of ovarian aging womens health brain aging and/or neurodegeneration. The position offers opportunities to develop expertise in animal models molecular biology tissue imaging flow cytometry single-cell genomics bioinformatics and translational aging research.

Responsibilities may include:

• Developing and leading research projects related to ovarian aging inflammation brain aging or neurodegenerative disease.
• Designing and performing experiments using mouse models tissue collection histology immunofluorescence flow cytometry molecular assays and/or sequencing-based approaches.
• Analyzing and interpreting experimental data including single-cell transcriptomic epigenomic or other multi-omic datasets depending on the candidates interests and expertise.
• Preparing manuscripts abstracts figures presentations and fellowship or grant applications.
• Presenting research findings at lab meetings institutional seminars and national or international conferences.
• Contributing to a collaborative and inclusive lab environment including mentoring junior trainees and working closely with other lab members and collaborators.

Minimum Qualifications

• Ph.D. in a biological science such as neuroscience physiology reproductive biology genomics bioinformatics chemistry physics or other relevant area M.D. or equivalent degree.
• Strong interest in womens health ovarian biology aging neurodegeneration inflammation or related areas.
• Experience with experimental design data analysis and scientific writing.
• Ability to work independently while contributing to a collaborative team environment.
• Strong communication organizational and problem-solving skills.

Preferred Qualifications

• Experience with one or more of the following areas: reproductive biology ovarian biology neuroscience aging biology immunology neuroinflammation Alzheimers disease or sex differences research.
• Experience with mouse models tissue dissection histology immunostaining microscopy flow cytometry molecular biology or sequencing library preparation.
• Experience analyzing RNA-seq single-cell RNA-seq ATAC-seq DNA methylation spatial transcriptomics or other high-dimensional datasets.
• Programming or data analysis experience in R Python or similar platforms.
• Evidence of productivity including first-author publications conference presentations or successful fellowship/grant applications.
• Interest in developing an independent research program related to aging womens health neurodegeneration or reproductive biology.

OMRF Overview
Founded in 1946 the Oklahoma Medical Research Foundation (OMRF) is among the nations oldest most respected independent nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases focusing on critical research areas such as Alzheimers disease cancer lupus multiple sclerosis and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nations leaders in patents per scientist.

Located in Oklahoma City a city that offers a dynamic and flourishing downtown area with low cost of living short commute times and a diversified economy OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a collective commitment to our mission . . . so that more may live longer healthier lives. Successful candidates will demonstrate commitment to this mission.

OMRF Benefits
We offer competitive salaries and comprehensive benefits to full-time employees including medical dental and vision insurance minimum 8% company retirement contribution vacation and sick leave and paid holidays. All employees have access to our onsite caf free onsite fitness center with access to personal trainer free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro. Learn more about our benefits here.

OMRF is an Equal Opportunity Employer.