Postdoctoral Fellow (Ranish)

Institute For Systems Biology

Job Location:

Seattle, OR - USA

Monthly Salary: Not Disclosed

Posted on: 5 hours ago

Vacancies: 1 Vacancy

Job Summary

The Ranish Group is seeking a highly motivated Postdoctoral Fellow to conduct research investigating

the transcriptional regulatory mechanisms underlying hematopoietic stem cell differentiation and how

defects in the process lead to diseases such leukemia and b-thalassemia. To accomplish this goal the lab

is developing mass spectrometry-based technologies to quantify the transcription factor proteome in

purified populations of differentiating erythroid cells. The data is being integrated with other

transcription-relevant -omics data to model the transcriptional regulatory networks underlying

hematopoiesis. The models are then used to guide experiments to understand how specific transcription

factors drive cell fate decisions. The successful applicant will be expected to design execute analyze

and troubleshoot the experiments.

This position is contingent upon funding expected to be received around July 2026.

Key responsibilities include

Development and application of mass spectrometry-based proteomics technologies
Recombinant protein expression and purification
Molecular biology assays
Discuss and present research at internal meetings
Manuscript preparation

Qualifications:

PhD in analytical chemistry or biomedical sciences (i.e. molecular/cellular biology or

biochemistry)

Strong interest in mass spectrometry-based proteomics and gene regulation
Ability to organize and prioritize work work efficiently and independently
Strong verbal and written communication skills

All ISB staff members are expected to have baseline technical skills and the ability to communicate

effectively and appropriately over email the intranet/forum etc. Employees should be able to use

Word Excel Outlook and PowerPoint at a functional level.

Benefits information: annual pay is $80169

ISB is a D/V/EOE.

The Ranish Group is seeking a highly motivated Postdoctoral Fellow to conduct research investigatingthe transcriptional regulatory mechanisms underlying hematopoietic stem cell differentiation and howdefects in the process lead to diseases such leukemia and b-thalassemia. To accomplish this goal the...