Early V&I In Vivo Scientist

Job Description

HereatAstraZenecayoullhave the opportunity to make a difference in peoples lives every day. As one of the worlds premier biotechnology companies our mission is centered on delivering life-changing products that advance worldhealth andhelp fight and cure disease. As aScientistin the Virology and Vaccines Discovery groupintheearly Vaccines & Immune Therapiestherapeutic areabasedinGaithersburg MDyoullplay a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients lives.

TheVirology and Vaccines Discoverygroup atAstraZenecaisdiscoveringand developing biologics and vaccines targeting key viral pathogens including respiratoryand chronicviruses.Weareconsistentlypushing the boundaries of science to deliver life-changing medicines to patients.Our deepexpertiseinvaccines and immunologyenables our ability to advancenovel therapeutic approachesand technologiesto prevent and treat infectious disease.Wehaveanindustry-leadingpipelineandoffer a unique and strong collaborative network as part of the AstraZeneca family.

Currently we areseekinga highly motivated and broadly skilled bench scientist within vivotechnicaland immunologyexpertiseanda track recordof scientific achievement to join the Virology and Vaccine Discovery group at AstraZeneca in Gaithersburg MD. Thescientist will be a key member of a team focused on developing next-generationvaccines andantibodiesthrough the drug discovery process. The position requires a strong interest invivarium andlaboratory bench worktodriveprojects forward.

AstraZenecahas a dynamic environment that fosters collaboration and innovation. We attract top minds and we nurture and build top talent.

Major responsibilities:

• Manage and conduct in vivo rodent studies to support the development of biologics and vaccines targeting viral pathogens of interest

• Performimmunizations andnecropsies collect and process tissues and blood products for downstream virologic and immunological assays

• Conduct in vitro virologic and immunological assays to support the development of biologics and vaccines including flow cytometry ELISpot and ELISA

• Design execute and interpret results from animal studies to characterize biologic therapies directed against viral infection as part of vaccine antigen discovery efforts

• Work collaboratively with colleagues across the organization (e.g.protein engineering bioinformatics pathology and translational medicine) to drive projects towards successful completion

Requirements/ Qualifications:

• B.S. in Virology Molecular Biology Microbiology Immunology Cell Biology or related scientific discipline with2 years of experienceor

• M.S. in Virology Molecular Biology Microbiology Immunology Cell Biology or related scientific discipline1

Specific skills:

Broad experiencedesiredinvirology molecularbiologyand/orimmunology

• Advanced knowledge ofanimal handling techniques including intramuscular intranasal subcutaneousand intravenous immunizationsandeuthanasia

• Advanced knowledge of tissue harvesting and processingi.e.lymph nodes spleen lung liver

• Experience with mouse tumor models is desired

• Knowledgeof flow cytometrysample acquisition and data analysisisstronglydesired

• Experience with automation is desired

• Ability to multitask and prioritizeamongnumerousprojects

• Strong interpersonal and collaborative skills together with evidence of having used these tosupport problem solving and delivery in a team-oriented collaborative environment

• Ability to work in a collaborative fast-paced environment while planning and meeting timelines

• Proventrack recordof success in your research and experience preparing written scientificreports (e.g.manuscripts) and oral presentations (e.g.slides posters)

• Strong verbal and written communication skills

Job complexity:Must be able to understandconductand interpret results of technically challenging experiments with supervision.

Supervision:Ability to work independently as well as part of team is expected.

To be considered for this exciting opportunity please complete the full application on our website at your earliest convenience.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability sex or sexual orientation pregnancy or maternity leave status race or national or ethnic origin age religion or belief gender identity or re-assignment marital or civil partnership status protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ieswhere the role is advertised.