Head of Gynaecological Cancers, Senior Global Medical Affairs Leader

Introduction to role

The Executive Director Global Medical Head (Cluster Lead) turns therapy area strategy into scalable highquality execution across a sophisticated cluster of indications and assets. Leading 56 Sr GMAL/GMALs who each own 12 indications this role ensures the ten core GMAL accountabilities are delivered consistently: strategic indication and asset leadership; crossfunctional global medical strategy; evidence generation; publication stewardship; scientific narrative and confidence building; medical education direction; external engagement and partnerships; and congress strategy and delivery. The Global Medical Head sets direction governs quality and ensures compliant efficient and highimpact medical execution globally in support of an anticipated 60 launches over three years across five tumor areas.

Ready to develop how evidence insight and strategy come together to redefine cancer care

Accountabilities

• Provide indication and asset leadership by translating therapy area priorities into clear indication strategies setting direction and making evidencebased tradeoffs across the cluster to benefit global medical objectives acting as final escalation point for sophisticated benefitrisk and reputational decisions.
• Drive global medical strategy through crossfunctional engagement by ensuring Sr GMAL/GMALs consistently lead key forums with markets and by standardising operating cadences that align Development Regulatory Pharmacovigilance Access and nonpromotional Commercial teams around the medical plan.
• Lead all aspects of evidence generation governance by mentoring and approving indication evidence plans that address the most critical gaps crafting strategy and develop of medical evidence (Phase IV pragmatic studies registries RWE IIS) and guiding operational support to deliver on time and on budget.
• Share accountability for publications by partnering with Publications on cluster publication strategies endorsing prioritisation authorship plans and timelines securing GPT/GPL endorsement and ensuring scientific integrity and compliance with GPP/ICMJE.
• Lead the crossindication scientific narrative by ensuring Sr GMAL/GMALs lead coherent narratives and confidencebuilding strategies that are consistent across channels geographies and lifecycle stages.
• Define medical education priorities at cluster level and provide subjectmatter guidance so medical training and communications teams can design develop and deliver education aligned to the scientific platform.
• Direct external engagement and partnerships strategy across indications being responsible for execution with KEEs societies and appropriate partners in alignment with MESO on partnership frameworks and governance.
• Lead congress strategy by defining the crossindication congress plan guiding symposia strategy abstracts booth scientific narratives compliant engagements and ensuring magnificent execution and robust postcongress insight collection.
• Enable regions and integrate insights by sponsoring toolkits core content and training establishing closedloop insight systems so market feedback rapidly updates strategy studies and content.
• Drive operational excellence by leading the cluster budget and vendor ecosystem setting standards for medical planning dashboards risk and issue management and MLR processes while optimizing FTE allocation across Sr GMAL/GMAL teams based on launch timing and complexity.
• Lead risk safety and compliance by anticipating scientific and safety risks partnering with Pharmacovigilance on signals RMPs and labeling updates and upholding medical governance promotional separation and auditready documentation.
• Act as an enterprise integrator by serving as senior medical counterpart to Development Regulatory/Labeling PV HEOR/Market Access Diagnostics/CDx Digital Manufacturing and regional medical leaders aligning with MESO on partnerships and medical excellence standards.

Essential Skills/Experience

• A minimum of a MBBS MD PhD or PharmD required; oncology specialty training or extensive oncology leadership experience strongly preferred. MPH/MBA advantageous.
• A minimum of 10 years in oncology Medical Affairs/Clinical Research with repeated global launch success; 5 years leading leaders (Sr GMAL/GMALs or Directors) and large matrixed portfolios across multiple indications/assets. Experience at country region and global setting are highly desirable.
• Deep knowledge of tumor biology standards of care and trial design; strong command of nonregistrational evidence (RWE/HEOR/PROs) publications governance congress strategy and biomarker/CDx environments.
• Portfolio prioritization evidencebased decision making executive influence stakeholder negotiation change leadership and talent development; excellent scientific communication.
• Proven strength operating within ICH/GCP PV processes GPP/ICMJE and global industry codes (e.g. EFPIA/PhRMA) with auditready discipline.

Desirable Skills/Experience

• Proven track record of orchestrating sophisticated launch portfolios across multiple tumor types or indications at global scale.
• Experience building or transforming highperforming medical teams through coaching senior leaders succession planning and capability development.
• Proven impact in shaping clinical practice or guidelines through evidence generation strategies that influence HTA bodies or professional societies.
• Strong record of partnership with Development and Commercial to resolve sophisticated benefitrisk issues and navigate challenging labeling or access environments.
• Comfort operating in fastpaced environments with multiple concurrent launches balancing strategic focus with handson problem solving.

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca Medical Affairs sits at the heart of transforming cancer care by fusing science with strategy to generate and communicate evidence that truly changes clinical practice. Colleagues collaborate across functions and geographies to translate deep scientific insight into realworld impact for patients at every point in their journey. It is an open environment where ideas are heard where brave thinking is encouraged and where active listening underpins how teams work together. Continuous learning is part of everyday work supported by a rich pipeline that offers stretching opportunities for those who want to grow their oncology careers while contributing directly to the ambition of eliminating cancer as a cause of death.

If this role matches your experience and ambitions apply now to help shape the future of oncology medicine worldwide.

The annual base pay for this position ranges from $285873 to $428809 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.