Senior Manager, Software Development Engineering

Labcorp is a global leader in diagnostic testing and drug development solutions helping healthcare providers researchers and patients make informed decisions that advance care. Join us in our mission to improve health and improve lives.

Work Schedule

This is a full-time exempt (salaried) position assigned to a First Shift schedule with standard business hours of Monday through Friday 8:00 a.m. to

5:00 p.m. in your local time zone. Business needs may occasionally require flexibility in work hours including earlier later or additional hours with reasonable notice provided when possible.

Applicants who live within 35 miles of either the Burlington NC or Durham NC location will follow a hybrid schedule. This schedule includes a minimum

of three in-office days per week at an assigned location either Burlington or Durham supporting both collaboration and flexibility.

Job Responsibilities

• Lead mentor and grow a team of software engineers across multiple levels (staff senior mid-level and junior) fostering a culture of technical excellence collaboration and continuous improvement

• Own the technical roadmap for variant classification systems aligning engineering priorities with business objectives and scientific needs

• Partner with product management data science variant science and bioinformatics stakeholders to define requirements set priorities and deliver

• impactful solutions

• Drive the design and delivery of tools that define store and provide meaningful variant sample and test-level information to support accurate variant interpretation and report generation

• Oversee development and maintenance of systems that translate raw bioinformatic data into variant and sample-level information including registration normalization observation groups and quality metrics

• Establish and maintain engineering standards processes and best practices across the team including code review testing CI/CD and incident response

• Manage team capacity hiring performance reviews career development and succession planning

• Drive architectural decisions that scale storage and processing of sample-level information to support growing data needs

• Champion automation of evidence placement and classification for variant interpretation

• Support test content and assay development initiatives through effective resource allocation and technical guidance

• Communicate technical strategy progress and risks to senior leadership and cross-functional partners

• Define and evolve the teams processes and governance for applying AI and LLM tools to variant classification workflows ensuring responsible use aligned with scientific rigor and regulatory requirements

• Remove blockers manage dependencies across teams and ensure timely delivery of commitments

Minimum Qualifications

• Bachelors degree

• 6 or more years of related professional software engineering experience

• 3 or more years in IT leadership roles

• 3 or more years experience managing software engineering teams including hiring performance management and career development

• 6 or more years experience and technical foundation in Python relational databases cloud platforms (AWS Azure or GCP) and modern web development frameworks

• 6 or more years demonstrated experience delivering complex software systems using RESTful APIs microservices architecture and CI/CD pipelines

• 3 or more years experience managing teams working with front-end technologies (e.g. React Angular JavaScript/TypeScript)

• 6 or more years experience and proven ability to define technical vision set priorities and drive execution across multiple concurrent workstreams

• 3 or more years experience and track record of building and developing high-performing engineering teams across multiple experience levels

Preferred Qualifications

• Masters Degree or Ph.D. in Bioinformatics/Computational Biology Computer Science or life sciences with 4 or more years related professional software engineering experience

• 5 or more years of engineering management experience including managing senior and staff-level engineers

• 5 or more years experience with bioinformatic tools annotation pipelines and genomic data resources (e.g. ClinVar gnomAD HGMD)

• 5 or more years experience with Spark text mining natural language processing semantic enrichment ontologies data mining or machine learning/AI

• 5 or more years experience with public-domain biomedical terminologies (e.g. MeSH NCIt HGNC)

Additional Job Standards

• Proven ability to define technical vision set priorities and drive execution across multiple concurrent workstreams

• Track record of building and developing high-performing engineering teams across multiple experience levels

• Familiarity with variant databases and the clinical variant interpretation landscape

• Experience translating complex scientific questions into information solutions and engineering roadmaps

• Experience managing teams in regulated or clinical environments

• Owns and delivers product or platform goals across multiple years and teams setting a high standard for technical outcomes team health and delivery

• Defines the vision scope and technical approach for large business-impacting projects with organization-wide implications

• Identifies prioritizes and drives solutions to ambiguous open-ended problems empowering the team to deliver with autonomy

• Influences the roadmaps of partner teams to align with and achieve broader business goals

• Serves as a role model for engineering leadership balancing technical depth with people management

• Effective verbal and written communicator with both scientific and non-scientific audiences including senior leadership

• Cultivates a team culture that leverages modern tools such as GitHub Copilot Claude Code or similar LLM tools to accelerate development testing and documentation

• Builds an inclusive psychologically safe team environment that attracts and retains top engineering talent

Labcorp is seeking a Senior Manager Software Engineering - Variant Classification to join our Labcorp Genetics team. This leader will build develop and manage a high-performing engineering team responsible for the systems and tools that power variant interpretation classification and report generation.

Application Window closes 5/8/2026

Pay Range: $140K - 198K annual salary

All job offers will bebased on a candidates skills and prior relevant experience applicabledegrees/certificationsas well as internal equity and market data.

The position is also eligible for an annual bonus under the Labcorp Bonus are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.

Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical Dental Vision Life STD/LTD 401(k) Paid Time Off (PTO) or Flexible Time Off (FTO) Tuition Reimbursement and Employee Stock Purchase Plan. Employees regularly scheduled to work less than 20 hours Casual Intern and Temporary employees are only eligible to participate in the 401(k) Plan. Employees who are regularly scheduled to work a 7 on 7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information please click here.

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race religion color national origin sex (including pregnancy childbirth or related medical conditions) family or parental status marital civil union or domestic partnership status sexual orientation gender identity gender expression personal appearance age veteran status disability genetic information or any other legally protected characteristic. Additionally all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.

We encourage all to apply

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