Synthetic DNA Process Development Scientist

Position Summary

We are seeking a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing. This role focuses on developing optimizing and scaling chemical processes for high-throughput and high-quality oligonucleotide production.

Key Responsibilities

Design develop and optimize chemical synthesis processes for nucleotides and oligonucleotides

  Process development and scale-up from R&D to manufacturing

Develop and improve oligonucleotide purification processes (e.g. HPLC ion-exchange desalting)

Troubleshoot synthesis and purification challenges to improve yield and purity

Collaborate with manufacturing QC and engineering for process transfer

Evaluate new chemistries and technologies

Author SOPs batch records and technical reports

Ensure compliance with quality systems

Mentor lab technicians

Qualifications :

Ph.D. or Masters degree in Organic Chemistry or related field (required)

Minimum 5 years of industrial experience in chemical synthesis

Experience with solid-phase oligonucleotide synthesis

Experience in oligonucleotide purification process development

Strong analytical skills (HPLC LC-MS)

Experience scaling processes to manufacturing

Preferred Qualifications

Experience in GMP or regulated environments

Familiarity with automated DNA/RNA synthesizers

Knowledge of modified nucleotides

Experience in high-throughput oligo production

Work Environment

Fast-paced collaborative environment

Ability to manage multiple priorities

Occasional off-hours support as needed

Additional Information :

Schedule:

• Monday-Friday 8:00am-5:00pm

• Weekend Work as needed

What we offer:

• Excellent full time benefits including comprehensive medical coverage dental and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Clinical Diagnostics is a Disabled and Veteran Equal Employment Opportunity employer.

Remote Work :

No

Employment Type :

Full-time