Process Chemistry Principal Scientist

Job Description

General Summary:

The Process Chemistry Principal Scientist is technically self-reliant with an extensive track record of accomplishments and will identify and solve complex problems repeatedly across a number of critical and diverse projects. This role will serve as an emerging technical expert in the field and provide reliable and valuable advice to project teams on a regular basis.

Key Duties and Responsibilities:

• Designs and performs sophisticated technically challenging experiments efficiently and independently ensuring compliance with applicable regulations and SOPs
• Generates effective hypotheses to pursue project goals and sets new experimental direction
• Identifies broad implications of results and their impact on overall study
• Develops novel and creative solutions to overcome project obstacles
• Makes substantive conceptual contributions to project activities and scientific strategies
• Provides authoritative technical recommendations broadly within the company regarding own discipline and occupies a key or pivotal formal or informal project role
• Serves as a practical manager of CRO interactions and external collaboration

Knowledge and Skills:

• Ability and track record of successfully working in cross-functional teams.
• Experience in drafting reviewing and submitting required documentation pertaining to the development and preparation of drug substances under cGMP environment
• In-depth conceptual knowledge of SOPs and GMPs and ensure compliance with all applicable regulations and SOPs.
• Experience and ability to draft CMC sections of INDs or CTAs is a plus.
• Experience in writing and transferring developed technology to outside CROs and working with suppliers to solve chemical issues for compound delivery.
• Excellent verbal and written communication skills to explain difficult or sensitive technical/scientific information and to prepare presentations and reports

Education and Experience:

• Bachelors degree in relevant field
• Bachelors degree and 10 years of experience or a Masters degree and 7 years of experience or a PhD and 4-7 years of experience or the equivalent combination of education and experience

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at