Global Medical Affairs Leader, TDR

Hybrid: 3 days a week onsite

The Global Medical Affairs Leader TDR is a pivotal strategic role at the centre of AstraZenecas ambition to transform cancer care worldwide. This position leads the medical strategy for assigned oncology indication(s)/asset(s) driving launch excellence shaping evidence generation and building confidence in our science across the globe. Acting as the key bridge between R&D and Commercial this role steers the Global Medical Plan orchestrates global launch readiness and ensures that every decision is grounded in robust data and patient impact. Ready to influence how new oncology medicines are understood adopted and scaled across diverse healthcare systems

Accountabilities

• Provide strategic medical leadership for assigned indication(s)/asset(s) owning the Global Medical Plan and leading launch strategy from early planning through postlaunch optimisation.

• Set clear strategic direction prioritise initiatives and make evidencebased tradeoffs to maximise patient outcomes and business impact adapting plans in response to external dynamics and performance against launch KPIs.

• Define track and interpret medical Key Performance Indicators to assess strategy impact identify progress and diagnose barriers to launch success.

• Represent Global Medical on key crossfunctional forums such as the Integrated Business Team and Global Product Team shaping commercial strategy informing R&D development and lifecycle planning and ensuring Medical input into clinical development and commercialisation strategies.

• Lead Medical Integrated Teams to align global regional and country medical teams around launch strategy and execution acting as a medical decisionmaker and ambassador in market engagements.

• Influence clinical development by identifying registrational evidence gaps companion study needs and Target Product Profile implications ensuring Medical perspectives shape Tumor Strategic Plans and Business Strategy Plans.

• Strengthen global medical capabilities through effective delegation coaching empowerment and mentorship building highperforming teams focused on launch excellence.

• Lead global and regional evidence gap analyses to define critical clinical realworld and mechanistic evidence needs and develop integrated evidence plans across clinical diagnostic digital and realworld sources.

• Shape the scientific and strategic design of AZsponsored interventional Medical Affairs studies conceptualise realworld evidence studies with partners and oversee governance milestones and resources to deliver to the highest scientific ethical and compliance standards.

• Own the Global Publications Plan from Phase 3 ID onwards in partnership with publications teams ensuring compelling credible scientific communications and appropriate review of local/regional medical studies and Externally Sponsored Research.

• Embed innovative approaches to evidence generation aligned with the MARS vision leveraging cancer networks novel study designs and datadriven insights.

• Own and lead the scientific narrative from prePhase 3 ID onwards ensuring consistency across evidence publications congresses and education while driving an Integrated Confidence Plan executed by Centres of Excellence.

• Define global medical education priorities identify key audiences and learning objectives guide delivery formats (digital hybrid inperson) and ensure scientific rigor in all educational activities.

• Lead the external engagement strategy for indication(s)/asset(s) including KEEs societies health systems and global organisations; gather insights that shape scientific practice and actively influence external experts to advance health outcomes and accelerate guideline adoption.

• Lead congress strategy endtoend: drive precongress planning (abstracts presentations training) guide onsite scientific presence and oversee postcongress insight synthesis dissemination and followup actions.

Essential Skills/Experience

• Advanced degree required (MD PhD PharmD in any related field)

• At least three years of experience within the pharmaceutical or biotech industry ideally at the country Region and global level.

• Demonstrated success in leading evidence generation strategies Medical Plans publications or scientific communication programs.

• Proven ability to influence senior stakeholders across Commercial R&D and Medical Affairs.

• Experience engaging external experts and scientific communities.

Desirable Skills/Experience

• Previous global Medical Affairs leadership experience in oncology.

• Experience leading crossfunctional teams in highly complex multiindication environments.

• Experience navigating launch environments new MoAs new CDx complex biomarker landscapes or challenging safety profiles (aligning to GMAL complexity criteria).

AstraZeneca offers an environment where scientific curiosity meets realworld impact: a global biopharmaceutical company tackling serious disease while constantly searching for new ways to solve complex healthcare and sustainability challenges. Teams reflect the diversity of the communities we serve; different perspectives are encouraged collaboration is expected and questioning minds are supported to push boundaries. With strong investment in learning data and digital innovation and crossfunctional partnerships inside and outside the organisation people are empowered to take smart risks learn fast from experience and contribute directly to lifechanging medicines for patients worldwide.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse teamrepresentingall backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.

The annual base pay for this position ranges from $206827.20 - 310240.80 USD Annual . Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles)to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay(as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.