Research Professional open rank intermediate, senior and principal

Job Summary:

The Burger laboratory in the Colorado Program for Musculoskeletal Research within the Department of Orthopedics is seeking to fill the position of a Research Services Principal Professional. Candidates may also be considered at intermediate or senior the Burger lab we are interested in early vertebrate development of the axial and lateral plate mesoderm using zebrafish and mice as models as well as associated structural birth defects such as spina bifida or defects affecting the heart/blood/bone/kidney. We are further interested in how the axial mesoderm develops into the intervertebral discs and associated underlying molecular mechanisms as well as intervertebral disc disease such as IVD degeneration.

The Research Services Principal Professional is expected to be the research lead for several ongoing projects including design of experimental setup data generation and data interpretation with the following key responsibilities:

Perform molecular biology experiments and related animal work including mouse husbandry genotyping tissue collection see details below (90% of work)

Perform administrative tasks see details below (10% of work)

Key Responsibilities:

All Levels

Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions

Utilize a variety of laboratory techniques required for research projects

Independently and creatively identify laboratory solutions

Independently Review develop and implement new or modified laboratory techniques required for research projects

Assist Team Leads Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives

Assist and train junior team members.

Senior Level: All Duties listed above plus the following:

Assist with developing or develop protocol-specific systems and documents including process flows training manuals and Standard Operating Procedures (SOPs). Maintains subject level documentation and prepares documents equipment and/or supplies

Assist with identifying issues related to operational efficiency and shares results with leadership

Provide laboratory science expertise and leadership in study design study oversight data management data analysis and manuscript preparation to assist all levels of investigators researchers and clinicians on new research activities across a wide range of disciplines

Serve as a resource to PIs and other stakeholders

Principal Level: All Duties listed above plus the following:

Oversee and provide informal leadership to the team members including managing day-to-day priorities evaluating and redistributing workloads on a temporary basis and mentoring staff

Provide input and feedback to leadership on team members overall performance performance evaluations opportunities for development and process improvement initiatives

Identify training and development opportunities for new and existing team members

Act as a Subject Matter Expert and authority in the area(s) of zebrafish laboratory work and development of the spine.

Additional Duties & Responsibilities:

Wet lab key responsibilities:

Conducting molecular biology experiments such as but not limited to: PCR gateway cloning restriction digest and T4 ligation Sanger sequencing of plasmid vectors RNA work e.g. CRISPR guide RNA generation mRNA generation immunohistochemistry/fluorescence Western blotting RNA and genomic DNA collection from mouse for RNAseq and ATACseq experiments

Work with different mouse mutant and transgenic strains such as mouse husbandry/breeding genotyping dissection for tissue collection e.g. spine long bones etc.

Mouse skeletal and non-skeletal tissue harvest for histological analysis including embedding sectioning and imaging and for RNA and genomic DNA preparation

Administrative responsibilities:

Ordering consumables and materials etc.

Maintaining laboratory area and equipment in working and clean condition

Contributing to animal protocol writing

Handling EHS requirements

Overseeing training from junior lab members

Managing internal and external collaborations with key stake holders

Presentation of research findings e.g. at department internal meetings national and international scientific meetings

Additional responsibilities related to position as assigned by PI

Work Location:

Onsite this role is expected to work onsite and is located in Aurora CO.

Why Join Us:

The University of Colorado Department of Orthopedics is a recognized global leader in the field and Colorados most trusted orthopedic group for adults and children. Our unique position at the forefront of medical science education and practice innovation translates in real-time to the most advanced patient care unmatched in Colorado and the Rocky Mountain Region. From routine cases to the most complex we treat every orthopedic condition including injuries and diseases of the bones joints nerves tendons ligaments and muscles across many orthopedic specialties.

Why work for the University

We haveAMAZINGbenefits and offerexceptional amounts of holiday vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability Life Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Minimum Qualifications:

Intermediate level:

Bachelors degree in biology molecular biology chemistry genetics or related field

- A combination of education and related technical/paraprofessional experience may be substituted for the bachelors degree on a year for year basis

One (1) year professional level wet lab research experience including mouse work

Senior level:

Bachelors degree in biology molecular biology chemistry genetics or related field

- A combination of education and related technical/paraprofessional experience may be substituted for the bachelors degree on a year for year basis

Two (2) years professional level wet lab research experience including mouse work

Principal level:

Bachelors degree in biology molecular biology chemistry genetics or related field

- A combination of education and related technical/paraprofessional experience may be substituted for the bachelors degree on a year for year basis

Three (3) years professional level wet lab research experience including mouse work

Preferred Qualifications

Masters degree in biology molecular biology chemistry genetics or related fiel

Four (4) years of experience in an experimental or wet laboratory including mouse woPrior experience with molecular biology methods including but not limited to PCR cloning immunoprecipitation microscopy RNA in situ hybridization

Prior experience with molecular biology methods including but not limited to PCR cloning immunoprecipitation microscopy RNA in situ hybridization etc.

How to Apply:

For full consideration please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references including name address phone number (mobile number if appropriate) and email address

Questions should be directed to: Alexa Burger .

Screening of Applications Begins:

Screening begins immediately and continues until position is filled. For best consideration apply by March 27 2026.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE

Intermediate: $50357-$64054

Senior: $54440-$69248

Principal: $62606-$79635

The above salary range (or hiring range) represents the Universitys good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator

Equal Employment Opportunity Statement:

CU is an Equal Opportunity Employer and complies with all applicable federal state and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity and we encourage individuals from all backgrounds to apply including protected veterans and individuals with disabilities.

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act please contact the Human Resources ADA Coordinator at .

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty staff students and visitors. To assist in achieving that goal we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and othervaccine preventable diseases. If you work visit or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work visit or volunteer addition if you work in certain research areas or perform certain safety sensitive job duties you must enroll in theoccupational health medical surveillance program.