Scientist, In Vivo Pharmacology, Inflammation Research

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist In Vivo Pharmacology Inflammation Research

What you will do

Lets do this. Lets change the this vital role you will work in a highly dynamic in vivo pharmacology teamexecutingin vivo preclinical disease models and in vitro assays in the vivarium and lab supporting pipeline programsmanaging interactions and presentation of results withproject teams and collaborators.

Key Responsibilities:

• Perform hands-on in vivo work primarily mice possibly rats and run concurrent studies
• Design experiments and execute studies working alongside senior scientists and associate scientists
• Generate high-quality experimental data and ensure studies are organized and prepared
• Supervise/coordinate associate scientists tasks/time as needed for study execution.
• Analyze and communicate results to project teams and the broader department
• Understand the biology of supported projects and contribute to project progression
• Participate in occasional weekend/evening dosing rotations as required.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The Scientist we seek is a driven pro-active independent and enthusiastic scientist who wants to contribute tocutting edgescience and serve patients in a highly productive team environment with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Masters degree and 2 years of Immunology or related experience

OR

Bachelors degree and 4 years of Immunology or related experience

Preferred Qualifications:

• PhD degree and post-doctoral training (or drug discovery experience) in the fields ofImmunology inflammation autoimmune disease or related disciplines.
• Strong understanding of Immunology andInflammationbiology and principles.
• Willingness and curiosity to learn and explore new areas of research.
• Experience executing in vivo preclinical respiratory disease modelsincludingasthma (OVA HDM) COPD (Elastase smoke extract) Bleomycin fibrosis (i.t.i.d.s.c.) respiratory virus infection (PR8) models preferred.
• Experience with preclinical inflammatory disease models including colitis lupus RA PBC important.
• Significant Experience with lung function measurements (FlexiVent Plethysmography)imaging (mCT) and inhaled drug deliverypreferred.
• Hands-on experience with in vivo techniques including dosing route of administration (i.v.i.p.p.o.i.n. i.t.r.o.i.d.s.c.) bleeds (r.o. cheek tail) necropsy (organ collection (intestine/colon lunglymphnodes spleen liver kidney skin) cardiac bleed lung BAL collection).
• Hands-on experience in cellular biochemical histological and molecular biology assay techniques ( MSD multi-color flow cytometry quantitative RT-PCR) preferred.
• Computer literacy especiallyproficiencywith GraphPad Prism ExcelPowerPointand Word.
• Attention to detail excellent organizational and communication killsaccurate& timelyrecordkeepingand data analysis are essential.
• Demonstratedtrack recordof independent critical thinking and scientific achievement.
• Demonstrated experience in andunderstandingof pharmacology with applicationusing invivo models of inflammation/Immunology.
• Experience working on project teams leading in vivo contributions.
• Ability to work in aflexibleteam-oriented and evening work may berequired.

What you can expect from us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race color religion sex sexual orientation gender identity national origin protected veteran status or disability status.

Salary Range