Research Fellow Neurology

Mayo Clinic

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profile Job Location:

Rochester, NH - USA

profile Monthly Salary: Not Disclosed
Posted on: Yesterday
Vacancies: 1 Vacancy

Job Summary

Description

The Nathan P. Staff Laboratory is seeking a highly motivatedPostdoctoral Fellow to investigate the cellular and molecular mechanisms of amyotrophic lateral sclerosis (ALS) using iPSCderived motor neuron models from patients with genetic forms of ALS. The fellow will design and execute experiments that combine advanced stemcell culture and differentiation CRISPRbased perturbations highcontent imaging electrophysiology and transcriptomic/proteomic analyses to dissect pathways in axonal transport RNA/protein homeostasis and to identify and validate therapeutic targets. Responsibilities include quantitative data analysis manuscript preparation presentation of findings at national meetings and collaborative work with clinicians bioengineers and computational scientists.

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars Research Scholars Professors Specialists and Student Interns sponsored by Mayo Clinic.



Qualifications
  • Must have a Ph.D. M.D. or equivalent doctoral degree in neuroscience cell biology bioengineering genetics or related field.

  • Handson expertise with human iPSC culture/differentiation strongly preferred.

  • Proficiency in one or more of CRISPR editing electrophysiology quantitative imaging or -omics; and a strong publication record.

  • The ability to work as a team player within and outside of the program.

  • We offer a collaborative wellresourced environment with access to stateoftheart core facilities competitive salary/benefits and individualized career development.



DescriptionThe Nathan P. Staff Laboratory is seeking a highly motivatedPostdoctoral Fellow to investigate the cellular and molecular mechanisms of amyotrophic lateral sclerosis (ALS) using iPSCderived motor neuron models from patients with genetic forms of ALS. The fellow will design and execute exp...
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Key Skills

  • Bioinformatics
  • Genetics
  • R
  • Biochemistry
  • Cell Biology
  • Research Experience
  • Statistical Software
  • Cell Culture
  • Molecular Biology
  • Data Analysis Skills
  • Flow Cytometry
  • Microscopy

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