Head of Project Toxicology

Purpose of the role

As the VP Head of Project Toxicology you will define and lead the safety assessment strategy across Evotec drug discovery and development portfolio ensuring robust sciencedriven decisionmaking from early concept through regulatory submission. Serving as the key interface between discovery and development safety you will shape the direction of our programs strengthen strategic partnerships and foster highimpact collaboration across diverse modalities and therapeutic areas. You will lead and develop a highperforming team of toxicology experts while working closely with senior leaders across the organisation and our global partners to deliver integrated forwardlooking safety strategies. This role may be based at any of our global sites with flexible working arrangements available.

Core accountabilities

• Own and advance the organisations safety strategy for both internal programs and external partnerships ensuring Evotecs toxicology framework remains innovative datadriven and scientifically robust.

• Inspire mentor and develop a team of expert toxicologists providing strong scientific leadership strategic direction and a culture of continual learning.

• Provide pivotal support to Discovery teams across small and largemolecule programs expertly guiding safety strategy from Target Safety Assessment through Development Candidate (DC) nomination.

• Serve as a trusted subject matter expert to Discovery and Development teams enabling effective design execution and interpretation of regulatory toxicology studies in support of Phase 1 clinical trials and beyond.

• Build and maintain collaborative trusted relationships with global clients aligning on safety strategy and ensuring seamless shared progress toward program objectives.

• Work closely with colleagues across internal functions to foster strong integration transparent communication and cohesive decisionmaking across the portfolio.

• Model and cultivate a culture of ownership trust accountability and empowerment across the team and broader organisation.

We are an equal opportunities employer and welcome applications from all suitably qualified persons regardless of their race sex disability religion/belief sexual orientation or age.

Capability Knowledge and Experience:

• Extensive seniorlevel experience in Toxicology gained within biotech pharma and/or CRO environments with a strong understanding of the strategic and operational demands of projectdriven organisations.

• Demonstrated leadership of interdisciplinary crossfunctional teams with the ability to influence motivate and align diverse scientific and operational groups within a complex matrix setting.

• Exceptional communication and scientific synthesis skills capable of integrating complex data to deliver clear actionable and riskbalanced recommendations to project teams partners and senior leadership.

• Proven track record of advancing programs from preclinical discovery into clinical development across multiple modalities and therapeutic areas.

• Deep expertise in preclinical drug discovery models with the ability to synthesise complex scientific strategies navigate uncertainty and align preclinical plans with development objectives.

• Highly skilled in managing challenging stakeholder dynamics resolving conflict and ensuring effective collaboration across discovery clinical regulatory and operational functions.

• Demonstrated experience in preparing and contributing to successful IND/CTA submissions for both smallmolecule and biologic programs.

• Comprehensive knowledge of global regulatory safety guidelines and their practical application across different modalities and therapeutic landscapes.

• Strong organisational and planning capabilities with meticulous attention to detail and effective timemanagement skills in a fastpaced environment.

• Creative strategic problemsolver with a growth mindset demonstrating adaptability curiosity and an openness to new approaches and emerging science.

Education and Qualifications:

• BSc MSc or PhD in Toxicology Pharmacology Biology or a related scientific discipline with substantial relevant experience.

• DBAT ERT UKRT or equivalent professional certification is desirable

FR : Dans le cadre de sa politique Diversité Evotec étudie à compétences égales toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy Evotec considers with equal competences all applications including people with disabilities.