Introduction to role
Are you ready to leverage technology to make a real impact on patients lives Do you want to apply your IT expertise to help a company turn science into lifechanging medicines Join us as aDirector ECS SAP Manufacturingat our Global Innovation and Technology Centre in Guadalajara Mexico.
AccountabilitiesAs a Director inIT Engineering you will bridge SAP architects/senior consultants and manufacturing operations translating plant needs into fittostandard SAP Manufacturing solutions with minimal customization. You will champion clean core and global template standards for agile shopfloor and planning enhancements across regions aligned with AstraZeneca QMS and pharmaceutical regulations.
- Fittostandard design:Lead designs for discrete and process manufacturing across ECC (PP PPPI QM PM) and SAP BUSINESS SUITE (embedded PP/DS DDMRP Fiori).
- Embed compliance by design:Integrate GMP/GxP data integrity (ALCOA) Annex 11/Part 11 concepts QA/CSV validation and controlled change management into process design.
- Mentorship:Cultivate and grow team talent through structured mentorship knowledge sharing and development planning.
- Master data and change control:Govern standards for materials BOMs/recipes routings/phases work centers/resources and inspection characteristics plus engineering change management.
- Shopfloor integrations:Orchestrate standardfirst integrations among S/4 DMC/MII EWM LIMS/PLM/IoT equipment; ensure validated interfaces and eventdriven data capture for batch records and release.
- Planning and scheduling:Optimize with PP/DS and DDMRP; minimize custom heuristics; plan changes with rehearsal and riskbased validation.
- Incident triage and resolution:Resolve MRP performance PP/DS constraints confirmations batch/serial inconsistencies QM holds and PM breakdown impacts while protecting the validated state and clean core.
- Analytics and controls:Deliver SAC manufacturing KPIs (OEE yield scrap schedule adherence) and ESGSFM metrics; automate controls via ICSM/IAG for audit readiness.
Essential skills/experience (Mandatory)
- Education:Bachelors degree in computer science information systems engineering or equivalent experience.
- Pharma manufacturing:Demonstrated experience in GMP/GxP environments batch records quality processes and validated system changes aligned to an AstraZenecalike QMS.
- SAP ECC core:Handson with PP or PPPI QM PM; strong understanding of master data and shopfloor execution.
- SAP BUSINESS SUITE manufacturing:Working knowledge of embedded PP/DS DDMRP Fiori; capability to apply standardfirst cleancore designs.
- Regulatory knowledge:Practical understanding of data integrity (ALCOA) Annex 11/Part 11 for electronic records and signatures QA/CSV deliverables.
- Integration:Experience with CPI/PIPO IDoc OData/REST; exposure to DMC/MII for shopfloor data capture and EWM/WMS for material movements; basics of LIMS/PLM integration.
- Agile delivery and validation:Delivery in validated plant environments coordinating rehearsals cutovers and hypercare with transport discipline and traceable evidence.
- Human skills:Excellent English communication (written and verbal) negotiation and influencing engagement with senior stakeholders in operations quality and engineering crisis/escalation management and proven mentoring/coaching.
Desirable (trainable) skills
- Thought Leadership:Track record of speaking engagements at reputable industry events and affiliation with meaningful professional organizations in the SAP manufacturing or pharmaceutical domain.
- PP/DS deepening:Constraintbased scheduling pegging strategies performance tuning and exception handling.
- DMC:Electronic batch record data capture esignatures rolebased Fiori apps for operators.
- QM advanced:Sampling strategies stability studies COA automation integration to deviations/CAPA workflows.
- PM advanced:Reliabilitycentered maintenance calibration processes integration of IoT telemetry.
- BRH:Manufacturing policy enforcement (recipe approvals batch release rules) without custom code.
- SAC:KPI design for OEE yield/scrap analytics deviations tracking; data modeling and storytelling.
- BTP:Sidebyside extensibility and lightweight shopfloor apps; RAP/Fiori/UI5 familiarity.
- ESGSFM:Sustainable manufacturing metrics and reporting alignment.
- ICSM/IAG:Automated control design and SoD models for shopfloor quality and maintenance roles.
- ATTP linkage:Awareness of how serialization impacts manufacturing and packaging workflows.
Success measures
- Fittostandard adoption: Minimal WRICEF and strong validation evidence.
- Stable plant operations: Smooth deployments with improved planning execution and quality metrics.
- Audit strength: Robust outcomes with consistent batch records and sustainability reporting via SAC and ESG solutions.
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Ready to take on this challenge and help redefine digital manufacturing Apply now.
Date Posted
19-feb-2026
Closing Date
12-mar-2026
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.
Required Experience:
Director
Introduction to roleAre you ready to leverage technology to make a real impact on patients lives Do you want to apply your IT expertise to help a company turn science into lifechanging medicines Join us as aDirector ECS SAP Manufacturingat our Global Innovation and Technology Centre in Guadalajara ...
Introduction to role
Are you ready to leverage technology to make a real impact on patients lives Do you want to apply your IT expertise to help a company turn science into lifechanging medicines Join us as aDirector ECS SAP Manufacturingat our Global Innovation and Technology Centre in Guadalajara Mexico.
AccountabilitiesAs a Director inIT Engineering you will bridge SAP architects/senior consultants and manufacturing operations translating plant needs into fittostandard SAP Manufacturing solutions with minimal customization. You will champion clean core and global template standards for agile shopfloor and planning enhancements across regions aligned with AstraZeneca QMS and pharmaceutical regulations.
- Fittostandard design:Lead designs for discrete and process manufacturing across ECC (PP PPPI QM PM) and SAP BUSINESS SUITE (embedded PP/DS DDMRP Fiori).
- Embed compliance by design:Integrate GMP/GxP data integrity (ALCOA) Annex 11/Part 11 concepts QA/CSV validation and controlled change management into process design.
- Mentorship:Cultivate and grow team talent through structured mentorship knowledge sharing and development planning.
- Master data and change control:Govern standards for materials BOMs/recipes routings/phases work centers/resources and inspection characteristics plus engineering change management.
- Shopfloor integrations:Orchestrate standardfirst integrations among S/4 DMC/MII EWM LIMS/PLM/IoT equipment; ensure validated interfaces and eventdriven data capture for batch records and release.
- Planning and scheduling:Optimize with PP/DS and DDMRP; minimize custom heuristics; plan changes with rehearsal and riskbased validation.
- Incident triage and resolution:Resolve MRP performance PP/DS constraints confirmations batch/serial inconsistencies QM holds and PM breakdown impacts while protecting the validated state and clean core.
- Analytics and controls:Deliver SAC manufacturing KPIs (OEE yield scrap schedule adherence) and ESGSFM metrics; automate controls via ICSM/IAG for audit readiness.
Essential skills/experience (Mandatory)
- Education:Bachelors degree in computer science information systems engineering or equivalent experience.
- Pharma manufacturing:Demonstrated experience in GMP/GxP environments batch records quality processes and validated system changes aligned to an AstraZenecalike QMS.
- SAP ECC core:Handson with PP or PPPI QM PM; strong understanding of master data and shopfloor execution.
- SAP BUSINESS SUITE manufacturing:Working knowledge of embedded PP/DS DDMRP Fiori; capability to apply standardfirst cleancore designs.
- Regulatory knowledge:Practical understanding of data integrity (ALCOA) Annex 11/Part 11 for electronic records and signatures QA/CSV deliverables.
- Integration:Experience with CPI/PIPO IDoc OData/REST; exposure to DMC/MII for shopfloor data capture and EWM/WMS for material movements; basics of LIMS/PLM integration.
- Agile delivery and validation:Delivery in validated plant environments coordinating rehearsals cutovers and hypercare with transport discipline and traceable evidence.
- Human skills:Excellent English communication (written and verbal) negotiation and influencing engagement with senior stakeholders in operations quality and engineering crisis/escalation management and proven mentoring/coaching.
Desirable (trainable) skills
- Thought Leadership:Track record of speaking engagements at reputable industry events and affiliation with meaningful professional organizations in the SAP manufacturing or pharmaceutical domain.
- PP/DS deepening:Constraintbased scheduling pegging strategies performance tuning and exception handling.
- DMC:Electronic batch record data capture esignatures rolebased Fiori apps for operators.
- QM advanced:Sampling strategies stability studies COA automation integration to deviations/CAPA workflows.
- PM advanced:Reliabilitycentered maintenance calibration processes integration of IoT telemetry.
- BRH:Manufacturing policy enforcement (recipe approvals batch release rules) without custom code.
- SAC:KPI design for OEE yield/scrap analytics deviations tracking; data modeling and storytelling.
- BTP:Sidebyside extensibility and lightweight shopfloor apps; RAP/Fiori/UI5 familiarity.
- ESGSFM:Sustainable manufacturing metrics and reporting alignment.
- ICSM/IAG:Automated control design and SoD models for shopfloor quality and maintenance roles.
- ATTP linkage:Awareness of how serialization impacts manufacturing and packaging workflows.
Success measures
- Fittostandard adoption: Minimal WRICEF and strong validation evidence.
- Stable plant operations: Smooth deployments with improved planning execution and quality metrics.
- Audit strength: Robust outcomes with consistent batch records and sustainability reporting via SAC and ESG solutions.
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Ready to take on this challenge and help redefine digital manufacturing Apply now.
Date Posted
19-feb-2026
Closing Date
12-mar-2026
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.
Required Experience:
Director
View more
View less