2-years researcher position, B cell malignancy
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Job Location:
Monthly Salary:
Posted on:
14 hours ago
Vacancies:
1 Vacancy
Job Summary
About the position
A researcher position funded by South-Eastern Norway Regional Health Authority for 2 year position is vacant. The researcher will work on ongoing projects investigating early lymphomagenesis at the interface between autoimmunity and B-cell malignancy including Cold Agglutinin Disease (CAD) anti-MAG polyneuropathy and cryoglobulinaemia type II. The project will be led by Senior researcher Agnieszka Malecka and the researcher will work in prof Ludvig A. Munthes group at the Department of Immunology and RCN CoE PRIMA University of Oslo. The research group is part of a stimulating and international research environment of about 100 scientists working on various aspects of immunology.
Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions and we encourage all qualified candidates regardless of background to apply!
Key information
Duties and responsibilities
The candidate will contribute to mechanistic studies of pathogenic B-cell clones development and preclinical evaluation of targeted biologics and translational analyses linking immune phenotypes to therapeutic response. Cellular characterization of pathogenic B-cell clones including B-cell receptor (BCR) analyses and immunophenotyping. Establishment and optimization of B-cell culture systems and functional assays to study clonal expansion signaling and antibody production. Participate in the development and preclinical evaluation of targeted biologics and other therapeutic strategies. Use and further development of xenograft models of B-cell lymphoproliferative disease for mechanistic and therapeutic studies.
Application
All applicants must apply through Webcruiter and include:
- Application letter.
- CV summarizing all relevant experience.
- Full list of publications.
- Copies of educational certificates and transcripts of records.
- Names and contact details of 2-3 references (include brief information of relation).
The application letter and CV should be in English or in a Scandinavian language. All other documents could be in English German French Italian or a Scandinavian the evaluation of the applications an emphasis will be placed on the applicants academic and personal qualifications good cooperative skills and the ability to successfully join a research team.
Qualifications
We seek a highly motivated candidate with a PhD or equivalent degree in immunology molecular biology hematology or a related biomedical discipline.
The ideal candidate will have:
- Documented research experience in B-cell malignancies and/or monoclonal IgMassociated diseases such as Cold Agglutinin Disease (CAD) anti-MAG polyneuropathy cryoglobulinaemia type II or related lymphoproliferative disorders.
- Strong background in B-cell biology including B-cell culture systems functional assays and immunophenotyping using multicolor flow cytometry.
- Experience in development and preclinical testing of targeted therapies or biologics.
- Experience with xenograft models of B-cell lymphoproliferative disease and in vivo experimental systems and in handling mice (FELASA C approval).
- Solid understanding of translational immunology including mechanisms linking autoimmunity and lymphomagenesis.
- Experience in data analysis and interpretation of complex immunological datasets.
Personal qualities
- Highly motivated and accurate.
- Good problem-solving skills.
- Ability to work as part of a team.
- Proficiency in English.
- Good writing skills.
We can offer
- An exciting and vibrant international scientific environment.
- Potential for personal and scientific growth.
- Membership in the Norwegian pension fund.
Address: Sognsvannsveien 20 0372 Oslo Norway
Contacts
About the employer
Required Experience:
IC
Key Skills
- Intelligence Community Experience
- Python
- Spss
- Microsoft Word
- R
- Regression Analysis
- Windows
- Stata
- Microsoft Powerpoint
- Research Experience
- Data Modeling
- Writing Skills
About Company
Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of na ... View more
