Research Fellow, Radiology Radiochemist
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Job Location:
Wake Forest, NC - USA
Monthly Salary:
$ 30 - 46
Posted on:
17 hours ago
Vacancies:
1 Vacancy
Job Summary
Department:
Status:
Benefits Eligible:
Hours Per Week:
Schedule Details/Additional Information:
M-F 8:00 AM - 5:00 PM. Hours could vary depending on grants workload.
Pay Range
$30.70 - $46.05Job Summary
The Radiochemist Postdoctoral Fellow is needed to fasten discovery-to-translation of novel molecular imaging agents by adding dedicated expertise in organic synthesis for radiotracer precursor design optimization and scale-relevant chemistry enabling higher success rates for in vivo imaging studies. This post-doc research fellow will work on to developing evaluating and designing novel PET imaging radiotracers for neurological disorders in rodent and nonhuman primate models. The candidate will also validate new biological methods to characterize their binding affinity in vivo ex vivo and in vitro using established lab protocols and resources.
Major tasks/activities will include:
Design and multi-step organic synthesis of radiolabeling precursors and reference standards
Radiochemistry translation support (precursor suitability for labeling stability impurity risk mitigation robust chemistry packages for reproducible runs)
Method development and documentation
SOP drafting reaction optimization records analytical methods (HPLC/GC/MS/NMR where applicable) reproducibility packages
Cross-functional collaboration with imaging scientists nuclear medicine/PET operations and disease-area investigators to move candidates from concept to clinical studies
Scholarly productivity & training: manuscripts abstracts presentations; mentoring trainees in synthesis/radiochemistry best practicessupporting Radiologys stated commitment to patient-centric care education and innovation/research.
Key Responsibilities:
Design and synthesize novel ligands for imaging of Alzheimers disease biomarkers.
Develop and optimize radiolabeling protocols
Perform in vitro and in vivo evaluation of probe specificity stability and pharmacokinetics.
Collaborate with neuroscientists pharmacologists and imaging specialists.
Requirements
PhD in Organic Chemistry Medicinal Chemistry Radiochemistry or Analytical Chemistry
Educational expertise
Expert in:
Organic synthesis of small molecules large peptides
HPLC GC TLC and NMR characterizations
Strong scientific writing and presentation skills
Troubleshooting in technical aspects of organic and analytical chemistry
Experience in handling radioactive materials will be an advantage
Our CommitmenttoYou:
Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs competitive compensation generous retirement offerings programs that invest in your career development and so much more so you can live fully at and away from work including:
Compensation
- Base compensation listed within the listed pay range based on factors such as qualifications skills relevant experience and/or training
- Premium pay such as shift on call and more based on a teammates job
- Incentive pay for select positions
- Opportunity for annual increases based on performance
Benefits and more
- Paid Time Off programs
- Health and welfare benefits such as medical dental vision life andShort- and Long-Term Disability
- Flexible Spending Accounts for eligible health care and dependent care expenses
- Family benefits such as adoption assistance and paid parental leave
- Defined contribution retirement plans with employer match and other financial wellness programs
- Educational Assistance Program
About Advocate Health
Advocate Health is the third-largest nonprofit integrated health system in the United States created from the combination of Advocate Aurora Health and Atrium Health. Providing care under the names Advocate Health Care in Illinois; Atrium Health in the Carolinas Georgia and Alabama; and Aurora Health Care in Wisconsin Advocate Health is a national leader in clinical innovation health outcomes consumer experience and value-based care. Headquartered in Charlotte North Carolina Advocate Health services nearly 6 million patients and is engaged in hundreds of clinical trials and research studies with Wake Forest University School of Medicine serving as the academic core of the enterprise. It is nationally recognized for its expertise in cardiology neurosciences oncology pediatrics and rehabilitation as well as organ transplants burn treatments and specialized musculoskeletal programs. Advocate Health employs 155000 teammates across 69 hospitals and over 1000 care locations and offers one of the nations largest graduate medical education programs with over 2000 residents and fellows across more than 200 programs. Committed to providing equitable care for all Advocate Health provides more than $6 billion in annual community benefits.
Required Experience:
IC
Key Skills
- Bioinformatics
- Genetics
- R
- Biochemistry
- Cell Biology
- Research Experience
- Statistical Software
- Cell Culture
- Molecular Biology
- Data Analysis Skills
- Flow Cytometry
- Microscopy
About Company
Proudly serving Wisconsin with 18 hospitals, over 150 clinics and 70 pharmacies across 30 communities. Choose Aurora Health Care for you and your family.
