Senior AI Scientist – Hit Discovery and Protein Sciences

Cambridge - UK

Monthly Salary: Not Disclosed

Posted on: 14 hours ago

Vacancies: 1 Vacancy

Job Summary

Job Title: Senior AI ScientistHit Discoveryand Protein Sciences

Location: Cambridge UK

Competitive salary and benefits

Introduction to the role:

Are you acuriousDataand AIScientist seeking a role where yourexpertisecan make an extraordinary impact This is an opportunity to join a dynamic and enthusiastic environment and transform the way we discoverhitsand protein reagentsin drug discovery.

Diverse Minds. Bold Disruptors. Meaningful Impactthrough Partnership.

At AstraZenecawerededicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit.Theresno better place to make a difference to medicinepatientsand society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learninggrowthand development.

Join a place built on innovation and creativity. We harness digital data science & AI to fast-forward our research. Your scientific vision would ensure that new small moleculesand peptidesdiscovered usingyour skillsandinpartnershipwith our technical platformscan serve as the seeds for future medicines and make a real difference in our mission to help patients.

You will be basedin early drug discovery R&DwithintheData Sciences & Quantitative Biologydepartmentin Discovery Sciencesand will work closely with our colleagues in the Hit Discoveryand Protein Sciencesdepartments.To learn more about our department and culture watch this video:A Life-changing day - Meet our Quantitative Biology team at AstraZeneca.

What you will do
You willdevelopdata science computational and AIsolutions to enablethe discovery ofhits(small molecules andpeptides)and protein reagentsenhancingthe output from ourhit andleaddatagenerationplatforms. This will involve close collaboration withscreeningscientistschemistsbiologistsinformaticians and statisticians. Wetruly believethat everyone hasan important rolein drug discoveryandeach individualbringsaunique set of competencies. Your curiosity and passion for personal development combined with support from colleagues and leaders will ensure you maximise your potential and contribution building from your current skills and experience.

Essential requirements:

Our team is a highly collaborative group of scientists working in an evolving technical and scientific landscape. Therefore you will be comfortable workingin a dynamic andteam-focussedenvironment. Critical will be tohave effective communication skills and a proactive and delivery-focused approach. Aligned to Hit Discoveryand Protein Sciencesactivities you will bring analytical skillsinnovationand your strategic mindsetto this excitingand evolvingarea.

You also have:

A PhD or equivalent numbers of years in industry/academia in bioinformatics cheminformatics computer scienceAI/MLstatisticsor related computationaland data sciencesubject areas applied tochemistrybiologyor medicine.

Experience in data science AI/MLand/or modellingmethods applied to the analysis of highly multidimensional or unstructured datasets inmolecular drug discovery orbiomedicalcontexts.

Programming in Python Rand/or Shell and experience with querying and integrating data from disparate sources (e.g. SQL NoSQLGraphorfile-based approaches).

Experiencein developingcomputational workflowsapplied to the analysis of experimentalorAI-generateddata(e.g.NextfloworSnakemake) knowledge of version control systems (e.g. Git and GitHub) and high-performance computing infrastructure.

Experiencereporting data analysis results drawingconclusionsand defining recommended actions in interdisciplinaryand collaborativeenvironments.

Desirables:

ExperienceinAI/MLand/or physics-based mathematical modelling methodsapplied topeptidessmall moleculesand/orproteins

Experience indata analysis of high-throughputassays (peptides /small moleculescreensvirtual orhigh content screening chemical profilingmass spectrometryrecombinant proteinexpressionand/oromics).

Experience in developing software and packages.

Track recordof publishing relevant researchaspreprintspeer-reviewed journals conferences and other scientific proceedings.

Ability to collaborate and build consensus across cross-functional teams.

Ability toidentifyopportunities and synergies across projects.

Experience incommunicatingchemistry and proteinconceptswithinadata sciencecontext.

Why AstraZeneca
There are many opportunities to develop yourself and your career. From our diverse portfolio and collaboration to our ground-breaking innovations itsa place for lifelong learning.

Youll be based in ourDiscoveryCentre placed in the heart of the Cambridge Biomedical Campus - an openwelcomingand vibrant centre that will encourage us and our partners to push the boundaries of scientific innovation.

Next Steps:

Are you already imagining yourself joining our team Good because we cant wait to hear from you. Please apply via the link and one of our team members will be in touch as soon as possible. This is being actively recruited so early application is advised.

Where can you find more

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Date Posted

20-Feb-2026

Closing Date

19-Mar-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.

Required Experience:

Senior IC

Job Title: Senior AI ScientistHit Discoveryand Protein SciencesLocation: Cambridge UKCompetitive salary and benefitsIntroduction to the role:Are you acuriousDataand AIScientist seeking a role where yourexpertisecan make an extraordinary impact This is an opportunity to join a dynamic and enthusiasti...