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Job Summary
The McAllister Lab is seeking a highly motivated lab technician to join our pioneering research efforts at the intersection of immunity aging patient diversity and cancer. Our labs research is focused on understanding how immune fitness and aging impacts breast cancer progression and response to therapy. By improving our understanding of the cellular and molecular mechanisms involving age-associated immune fitness in disease control the McAllister Lab aims to develop innovative personalized therapeutic treatments and strategies that benefit breast cancer patients and account for their diversity.
We are looking for an entry-level lab technician with a background in biological research data science and R programming and the ability to independently complete lab tasks in a dynamic research this role the individual will focus on supporting our research endeavors through the computational analysis of new and existing data derived internally and externally with occasional experimental support of work using mouse models cell and molecular biology and histology.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
- (70%) Reporting to the Computational Lead support computational efforts in the lab through analysis of internal and external datasets using R programming.
- Use dry-lab techniques for analyzing -omic-level datasets including differential gene expression analysis regression-based modeling and visualization to derive biological insights as part of individually led and collaborative projects in the lab.
- Effectively communicate findings to a cross-functional multidisciplinary research team of bench scientists computational biologists and clinicians.
- Support manuscript production and grant writing by providing written methodological language and informative visualizations.
- Maintain proper documentation of scripts using gold-standard practices for version control and code production. Maintain GitHub repositories validate code and ensure generalizability of scripts to other data. Keep code well commented and easy to implement.
- (20%) Support bench science efforts investigating aging and breast cancer.
- As part of a collaborative team of instructors graduate students and postdocs develop and perform wet lab techniques as needed.
- Following established protocols and standard operating procedures assist senior lab personnel with in vitro ex vivo and in vivo tasks including but not limited to cell culture qPCR and tissue processing for analytical molecular biology assays.
- Maintain a detailed and accurate electronic lab notebook documenting efforts.
- (10%) Contribute to lab operations
- Assist with inventory operational tasks and ordering on an as-needed basis. Keep organized records and data storage structures in shared file drives.
- Contribute to routine lab responsibilities including weekly lab meetings and monthly journal clubs.
QUALIFICATIONS:
- Bachelors degree in biology or related major required.
- laboratory and computational experience.
- Eagerness to learn and build skills in both wet and dry lab settings.
- Excellent verbal and written communication skills.
- Experience running troubleshooting and planning experiments.
- Cell culture experience preferred.
SKILLS/ABILITIES/COMPETENCIES REQUIRED:
- Team player willing to collaborate and ask questions.
- Good organizational skills detail oriented.
- Sound degree of computer literacy including Microsoft suite and intermediate R programming.
- Ability to methodically record data and to analyze data using basic and intermediate statistics.
- Demonstrated professionalism.
- Work independently after initial training with minimum supervision. Discusses progress of work regularly with supervisor.
WORKING CONDITIONS:
Requires work in an environment where animals are used for research. Position may at times require the employee to work with or be in areas where hazardous materials are present.
Additional Job Details (if applicable)
Onsite
4-6 Blackfan Circle
40
Regular
Day (United States of America)
Pay Range
$20.16 - $29.01/Hourly
Grade
5
At Mass General Brigham we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive and any offer extended will take into account your skills relevant experience if applicable education certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however it does not encompass all elements contributing to your total compensation addition to competitive base pay we offer comprehensive benefits career advancement opportunities differentials premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
2200 The Brigham and Womens Hospital Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religious creed national origin sex age gender identity disability sexual orientation military service genetic information and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact Human Resources at .
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