Exec Director, Drug Metabolism

At Gilead were creating a healthier world for all people. For more than 35 years weve tackled diseases such as HIV viral hepatitis COVID-19 and cancer working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the worlds biggest health challenges and our mission requires collaboration determination and a relentless drive to make a difference.

Every member of Gileads team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions and were looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future you are the key driver in evolving our culture and creating an environment where every employee feels included developed and empowered to fulfil their aspirations. Join Gilead and help create possible together.

Job Description

Job Title: Executive Director Drug Metabolism and Pharmacokinetics (DMPK)

Job Type: Regular Full-Time

Location: Foster City CA

Specific Responsibilities:

The primary responsibility of this Biologics DMPK Executive Director position is to serve as an expert in the PK of biologics representing the DMPK department by providing strategic and scientific leadership on large molecule discovery and development project teams. The position includes the responsibility for the design supervision and interpretation of experiments to understand the absorption distribution metabolism and excretion (ADME) properties of large molecule protein addition to serving as a project representative and departmental expert he/she will have the opportunity to participate on business development and external research projects.

Essential Duties and Job Responsibilities:

• Serve on project teams at various stages of discovery and development as a subject matter expert and scientific leader for DMPK Biologics providing PK or PK/PD expertise to the design of nonclinical PK toxicology or pharmacology studies.

• Participate in business development and licensing evaluations.

• Prepare study protocols and coordinate execution of nonclinical studies which may involve multiple functional areas and CROs.

• Design and perform complex PK-PD analysis to answer translational questions in support of project deliverables and first-in-human dose predictions.

• Interpretation and strategy for evaluating the impact of anti-drug antibody (ADA).

• Work closely with project teams line management and CROs to assure high quality and timely delivery of written PK reports and regulatory documents (IND IMPD IB BLA) for regulatory submissions.

• Supervising of research scientists and associate scientists may be required.

Knowledge Experience and Skills:

• Requires a highly motivated individual with a PhD and 20 years of post-graduate industry experience in the fields of pharmacokinetics drug metabolism pharmaceutics or related life science field primarily supporting the PK characterization of large molecule/biologics through discovery and development.

• Applicant must demonstrate excellent verbal and technical communication independent scientific thinking with the ability to interpret results determine next steps and present data to project teams and senior management.

• Applicant must demonstrate intellectual curiosity and propensity to stay current with latest advances in DMPK of biologics and PK analysis with a proven track record of sustained external visibility through publications presentations and/or involvement in professional organizations.

• Applicant must be highly experienced in the application of PK-PD and multi-compartmental modeling.

• Knowledge in the application of large molecule/biologics ligand binding assays and LC/MS bioanalysis is highly desirable.

For additional benefits information visit:

Eligible employees may participate in benefit plans subject to the terms and conditions of the applicable plans.

For jobs in the United States:

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment and is dedicated to fostering an inclusive work environment comprised of diverse perspectives backgrounds and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race color religion national origin sex age sexual orientation physical or mental disabilitygenetic information or characteristic gender identity and expression veteran status or other non-job related characteristics or other prohibited grounds specified in applicable federal state and local order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Era Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact for assistance.

For more information about equal employment opportunity protections please view theKnow Your Rights poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about discussed or disclosed their own pay or the pay of another employee or applicant. However employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information unless the disclosure is (a) in response to a formal complaint or charge (b) in furtherance of an investigation proceeding hearing or action including an investigation conducted by the employer (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.