Senior CTMS Delivery Product Manager (Salesforce)

Role Overview

The Senior CTMS Delivery Product Manager is responsible for technical delivery system design coherence and architectural integrity of the Salesforce-based Clinical Trial Management System (CTMS) including Cloudbyz components.

This role sits within the technology organization and serves as the technical design authority for CTMS delivery ensuring that ClinOps-owned business decisions and outcomes are implemented using a holistic end-to-end system architecture that supports scalability compliance and long-term maintainability.

The role focuses on how CTMS changes are designed and delivered technically while system roadmap and final business decisions remain with Clinical Operations consistent with the CTMS governance model .

Key Responsibilities

CTMS Technical Architecture & System Design

(IT Delivery Accountability ClinOps Consulted)

• Act as the CTMS Technical System Architect for Salesforce and Cloudbyz implementations

• Maintain a holistic architectural view of the CTMS platform across:

  • Study site subject and financial modules

  • Integrations with EDC eTMF IRT ERP and analytics systems

• Evaluate proposed changes for cross-module cross-study and cross-system impacts

• Define and enforce technical design standards data models and integration patterns

• Prevent fragmented study-specific configurations that introduce technical debt

Architectural accountability is technical delivery-focused and does not include ownership of business processes system outcomes or regulatory risk which reside with ClinOps .

CTMS Delivery & Execution

(IT Accountable Cloudbyz Responsible under IT)

• Serve as the IT delivery owner for CTMS enhancements and platform changes

• Execute delivery against a ClinOps-defined and approved CTMS roadmap

• Manage Cloudbyz as an IT vendor ensuring execution aligns with internal architectural standards

• Lead Agile delivery activities including backlog refinement sprint planning and release execution

• Balance configuration vs. customization decisions to support scalability and maintainability

Business Intake & Translation (Design-Governed)

(ClinOps Accountable IT Responsible for Translation)

• Partner with Clinical Systems and business stakeholders to:

  • Review approved change requests from a system-design and delivery feasibility perspective

  • Translate requirements into technically sound user stories and acceptance criteria

• Surface architectural risks and recommend alternative technical approaches when business requests may compromise system integrity or scalability

Salesforce Technical Leadership

(IT Responsible)

• Provide technical product leadership across:

  • Salesforce configuration customization automation and reporting

  • Cloudbyz CTMS modules and extensions

• Coordinate and oversee integrations to ensure data consistency and architectural alignment

• Collaborate with developers architects and vendors to ensure adherence to CTMS delivery standards

Compliance Support & Validation-Ready Delivery

(Quality Accountable IT Supports)

• Design and deliver CTMS changes that support:

  • GxP principles

  • 21 CFR Part 11 requirements

  • Validation and audit readiness

• Partner with Quality and Clinical Systems to support CSV activities recognizing that validation accountability resides with Quality

Stakeholder Communication & Delivery Governance

(Shared Governance Model)

• Communicate delivery status architectural decisions and technical risks to:

  • Clinical Systems leadership

  • IT leadership

• Serve as the escalation point for technical design and delivery conflicts

• Proactively identify systemic design issues and delivery risks before they impact production or compliance

Required Qualifications

• 10 years of experience in technical product management system architecture or enterprise application delivery

• Hands-on experience designing and delivering Salesforce-based platforms

• Strong experience with CTMS platforms

• Proven ability to act as technical design authority while operating within a business-owned governance model

• Experience in GxP-regulated environments with validated systems

Preferred Qualifications

• Experience combining delivery ownership and system architecture responsibilities

• Familiarity with EDC eTMF IRT safety and financial systems

• Salesforce certifications (Admin Platform App Builder Integration Architecture Designer)

• PMI Certification

OUR OPPORTUNITY

Natera is a global leader in cell-free DNA (cfDNA) testing dedicated to oncology womens health and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer healthier lives.

The Natera team consists of highly dedicated statisticians geneticists doctors laboratory scientists business professionals software engineers and many other professionals from world-class institutions who care deeply for our work and each other. When you join Natera youll work hard and grow quickly. Working alongside the elite of the industry youll be stretched and challenged and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical dental vision life and disability plans for eligible employees and their dependents. Additionally Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave 401k benefits commuter benefits and much more. We also offer a generous employee referral program!

For more information visit .

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment and welcome people of different backgrounds experiences abilities and perspectives. Inclusive collaboration benefits our employees our community and our patients and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply and will be considered without regard to race color religion gender gender identity or expression sexual orientation national origin genetics age veteran status disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories consistent with applicable laws.

If you are based in California we encourage you to read this important information for California residents.

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