Senior Scientist I, Analytical Development

The Senior Scientist I Analytical Development at LGC AxoLabs will serve as a subject matter expert (SME) in analytical method development and validation for oligonucleotide drug substances within a Contract Manufacturing Organization (CMO) environment. This role involves leading analytical initiatives providing technical guidance to cross-functional teams and engaging with clients to ensure the accurate characterization and in-process testing of oligonucleotide API and raw materials in compliance with regulatory standards.

LGC AxoLabs has an extensive ever-evolving global client base and impressive technical capabilities within a state-of-the-art GMP facility. As the organization continues to grow we seek technically adept and highly motivated candidates who can contribute to innovative solutions in oligonucleotide analytical development. The successful candidate will be detail-oriented proficient in advanced analytical chemistry techniques and experienced in oligonucleotide analysis. This role requires strong problem-solving skills technical leadership and direct interaction with clients to support their project needs.

Qualifications :

Routine tasks include leading analytical HPLC method development validation and other analytical studies (e.g. forced degradation MS/MS sequencing stability) for custom oligonucleotide APIs and raw materials. The Senior Scientist I is responsible for managing multiple development projects leading technical discussions and facilitating fulfilment of project deliverables according to established timelines.

To perform this job successfully an individual must be able to perform each essential function satisfactorily.

Essential Functions: 

• Serve as a subject matter expert (SME) in analytical HPLC method development and validation for oligonucleotide APIs and raw materials.
• Independently design execute and interpret complex analytical studies including forced degradation MS/MS sequencing and stability studies.
• Lead technical discussions with internal teams and clients to define analytical strategies troubleshoot challenges and drive project deliverables.
• Author and review technical documentation including method development reports validation protocols Standard Operating Procedures (SOPs) and regulatory submission materials.
• Collaborate with cross-functional teams (e.g. Process Development Quality Control and Manufacturing) to integrate analytical solutions into oligonucleotide production workflows.
• Maintain working knowledge of relevant regulatory and pharmacopeia guidelines (FDA/ICH/USP) to ensure compliance across analytical activities.
• Provide mentorship and technical guidance to junior scientists supporting skill development and scientific excellence within the team.

Other Skills and Abilities:

• Self-starter with strong problem-solving skills and the ability to work independently and collaboratively within cross-functional teams.
• Strong communication skills both written and verbal to effectively present data and collaborate with internal teams and external partners.
• Ability to manage multiple analytical projects simultaneously while maintaining attention to detail and deliverable timelines.
• Demonstrated commitment to scientific excellence and alignment with LGCs core values and quality standards.

Education/Experience: 

• Bachelors degree in Chemistry Biology Biochemistry or related discipline with 7 years of applicable experience or Masters degree with 5 years or Ph.D. with 03 years of experience in a related field.
• Advanced technical understanding of oligonucleotide manufacturing processes and hands-on experience with relevant analytical techniques (i.e. HPLC-MS GC-FID etc) and equipment.
• Working knowledge of chromatography and/or other software including ChemDraw JMP Empower MassLynx Chromeleon and/or Waters Connect.
• Prior experience in a GMP-regulated environment within a CMO/CDMO or pharmaceutical manufacturing setting is strongly preferred.

Additional Information :

What we offer (US based-employees):

• Competitive compensation with strong bonus program
• Comprehensive medical dental and vision benefits for employees and dependents
• FSA/HSA Pre-tax savings plans for health care childcare and elder care
• Deductible Buffer Insurance and Critical Illness Insurance
• 401(k) retirement plan with matching employer contribution
• Company-paid short- and long- term disability life insurance and employee assistance program
• Flexible work options
• Pet Insurance for our furry friends
• Enhanced Parental leave of 8 additional weeks
• PTO that begins immediately
• Town Hall monthly meeting onsite/virtual Cheer program where employees are recognized for outstanding work Company wide social events frequent catered lunches and much more!

The typical pay range for this exempt role is:

Minimum: $ 93750 /Salary

Maximum: $ 156250 /Salary

This range represents the low and high end of the anticipated salary range for the California -based position.  The actual base salary will depend on several factors such as: experience skills and location.

LGC strongly believes that every job applicant and employee should be valued for their individual talents regardless of age disability race color ethnic or national origin sex sexual orientation gender reassignment marital or civil partnership pregnancy or maternity religion or belief. Short listing interviewing and selection will always be carried out without regard to gender sexual orientation marital status color race nationality ethnic or national origins religion or belief age or trade union membership

Remote Work :

No

Employment Type :

Full-time