Principal Research Scientist I or Senior Scientist II, Biologics Analytical Research and Development, CMC Biologics Development

AbbVie Biologics Analytical Research & Development (Biologics Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVies pharmaceutical products. Our scope includes AbbVies diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVies pipeline of innovative medicines. Careers in AbbVie Biologics Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.

The biologics characterization group develops state-of-the-art analytical techniques for in-depth characterization of therapeutic proteins and other novel biologic molecules using advanced combined analytical techniques. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Key Responsibilities

•  Serve as a subject matter expert in BioARD lead phase-appropriate analytical development strategies for biologics characterization including ADC multi-specific antibodies and other novel modalities.
•  Design and execute the buildout of chromatography and/or mass spectrometry methods for extended characterization product release stability comparability and in-process analytics.
•  Make lab-based data-driven contributions to project team and deliver results in a team-oriented setting and will work across scientific disciplines to drive programs through critical milestones.
•  Represent key area function in cross-functional project teams provide hands-on analytical support technical oversight to portfolios.
•  Collaborate and integrate scientific objectives associated with development of new/improved products or technology; contribute to internal scientific exchange and publications.
•  Author review lab notebook analytical report and analytical sections of regulatory filings. Primary author of external publications presentations regulatory documents and/or primary inventor of patents. Present at leading scientific conferences.
•  May mentor/supervise a team of one or more guide and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals.

Qualifications :

Principal Research Scientist I:

•  PhD in scientific discipline (e.g. Analytical Chemistry Biochemistry or Biology) with 6 years of industry experience 
• Proficiency and direct experience in large biologics characterization and separation techniques including various chromatography analytical methods (SEC/HIC/RPLC/IEC) intact or subunit mass analysis peptide mapping.
•  Knowledge in key analytical CMC areas such as risk-based analytical development and method validation CQAs reference standard qualification specifications comparability.
•  Familiarity with biologics CE icIEF biophysical assays or binding and functional assays are plus.
•  Working knowledge of lab automation good written and oral communication skills time management skills.
•  Ability to work independently and collaboratively across functions.

Senior Scientist II:

•  PhD in scientific discipline (e.g. Analytical Chemistry Biochemistry or Biology) with 4 years of industry experience OR
• Masters degree in related fields with 8-10 years of industry experience
• Proficiency and direct experience in large biologics characterization and separation techniques including various chromatography analytical methods (SEC/HIC/RPLC/IEC) intact or subunit mass analysis peptide mapping.
•  Knowledge in key analytical CMC areas such as risk-based analytical development and method validation CQAs reference standard qualification specifications comparability.
•  Familiarity with biologics CE icIEF biophysical assays or binding and functional assays are plus.
•  Working knowledge of lab automation good written and oral communication skills time management skills.
•  Ability to work independently and collaboratively across functions.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this postingbased on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately paymore or less than the posted range. This range may be modified in the future. 

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commissionincentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and untilpaid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time