Principal Scientist, In Vivo Pharmacology

Job Description

Principal Scientist (R5) Quantitative Biosciences In vivo Pharmacology

The Discovery Quantitative Biosciences (QB) in vivo Pharmacology team at Boston is looking for an initiative-taking and experienced Principal Scientist with a strong background in Immunology and In Vivo Pharmacology. The successful candidate is expected to drive scientific excellence in the implementation of inflammation/autoimmune model development in vivo PK/PD and efficacy studies while serving as a key intellectual contributor in the conception and execution of discovery projects. The role will involve significant interaction and collaboration among various functional groups in a highly matrix system and with external partners.

The successful candidate will lead in vivo scientists to:

• Perform experiments using preclinical species to support the discovery and clinical development of novel immunology compounds.

• Manage external studies at CROs and academic collaborators including monitoring study execution and ensuring finalization of study reports within set timelines.

• Manage a group of in vivo scientists providing guidance mentorship accountability and professional development opportunities.

• Serve as a scientific leader in the Quantitative Biosciences (QB) department at Boston partnering and aligning with our global network-wide organizational objectives and ensuring that we remain at the forefront of drug discovery.

• Represent the QB/Pharmacology functional area at therapeutic area governance forums program teams due diligence exercises and/or cross-functional teams as needed.

• Foster a culture of innovation and continuous improvement within the QB/Pharmacology team driving the development and adoption of new methodologies and technologies.

• Ensure compliance with company established practices and procedures including laboratory notebooks computer files quality and regulatory guidelines and safety standards.

EDUCATION:

• PhD in Immunology Pharmacology Biology Biotechnology Molecular and Cell Biology Biochemistry Bioengineering or related STEM field with 7 years of industry / biotech experience in immunology drug discovery or an MS with 10 years of experience or a BS with 14 years of experience.

REQUIRED SKILLS:

• Experience using preclinical models to evaluate the in vivo pharmacology of novel immunology and/or inflammation drugs.

• Proven managerial/supervisory experience with a track record of training developing talent and mentoring team members in the field of Immunology/pharmacology and drug discovery.

• Proficiency in complex problem-solving and the ability to influence strategy across organizational boundaries.

• Strong skills in strategic thinking effective communication collaboration balanced risk-taking and a relentless pursuit of excellence.

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Effective September 5 2023 employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week Monday - Thursday although the specific days may vary by site or organization with Friday designated as a remote-working day unless business critical tasks require an on-site Hybrid work model does not apply to and daily in-person attendance is required for field-based positions; facility-based manufacturing-based or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.

The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

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