Senior Scientist
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Job Location:
Gaithersburg, MD - USA
Monthly Salary:
$ 108474 - 162710
Posted on:
7 hours ago
Vacancies:
1 Vacancy
Job Summary
Senior Scientist
Introduction to role
We areseekinga highly motivated Senior Scientist with extensiveexpertisein cancer immunology/immunotherapy. The successful candidate will have substantial experience in studying T cells and myeloid cellsboth in vivo and in vitro with a specific interest in myeloid cell progenitors and/or lipid metabolism. You will independently design and execute projects/experiments troubleshoot andoptimizemethods andgenerate interpret and report scientific data clearly and concisely. A PhD in Immunology or a related field and a proven postdoctoral record with strong publications arerequired. Strongexpertisewith mouse tumor models is is an onsite role requiring 5 days per week of onsite presence.
As a Senior Scientist in our Oncology R&D department you will be a key member of a team focused on designing novel therapeutics to target myeloid biology and immunotherapy supporting projects through the drug discovery and development process. You will bring your theoretical and practicalexpertisein immunology toestablishassay systems and deliver datasets that will have a direct impact on immune-oncology therapeutics.
Accountabilities
Independently conductmechanisticcancer immunology and drug discovery research experiments using techniques in immunology molecular and cellular biology
Assess and report data with little guidance in a clear and concise manner with a strong understanding of its implications within the overall context of drug discovery
Maintain a well-developed understanding of approaches to investigate the function of myeloid cells and aspects of drug discovery
Actively liaise between programs/departments sharing scientific knowledge and feedback on others experiments to ensure efficient relay of information and translation of data
Ensure own work and work of peers is compliant with Good Laboratory Practice Safety Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations
May be asked to lead or co-lead a project team and contribute to scientific publication goals
Essential Skills/Experience
A PhD in immunology cancer biology or related fieldwith minimum of 2 years of experience
Extensive experience in studying T cells or myeloid cells: MDSC macrophages dendritic cellsexpertiseor knowledge of peptide vaccines
Strong hands-on skills in basic biochemical and immunological methods including multi-color flow cytometry (FACS) ELISA/multiplex assays western blotting luminescence assays cell killing assays high content imaging
Excellent organizational and communication skills
Ability to work in a high-paced team environment plan and meet timelines
Proventrack recordof success in your research and experience preparing written scientific reports (e.g. manuscripts) and oral presentations to broad and diverse audiences
Desirable Skills/Experience
In vivoexpertisein murine tumor models
Experience developing cancer immunotherapy including cancer vaccines and cellular therapies
At AstraZeneca we follow the science and pioneer new frontiers. Join our team dedicated to Oncology with an ambition toeliminatecancer as a cause of death. With multiple indications and high-quality molecules at all stages of our innovative pipeline we keep pushing forward. Fusingcutting-edgescience with the latest technology to achieve breakthroughs. Backed by investment we aim to deliver 6 new molecular entities by 2025. Our environment is built on courage curiosity and collaboration. We make bold decisions driven by patient outcomes. Empowered to lead at every level free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Pioneers of collaborative research we have built an unrivalled scientific community both internally and externally. Working seamlessly together weexpediteresearchinsome of the hardest-to-treat the opportunity tobuild a rewarding career as part of the team committed to improving the lives of millions with cancer.
Ready to make a difference Apply today!
The annual base pay for this position ranges from $108474 to $162710. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs paid time off (i.e. vacation holiday and leaves) as well as health dental and vision coverage in accordance with the terms of the applicable plans.
Date Posted
22-Jan-2026Closing Date
04-Feb-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Required Experience:
Senior IC
Key Skills
- Laboratory Experience
- Mammalian Cell Culture
- Biochemistry
- Assays
- Protein Purification
- Research Experience
- Next Generation Sequencing
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more
