Shared Resources Specialist II Mouse Development Lab (MoDeL)

Fred Hutchinson Cancer Center is an independent nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation HIV/AIDS prevention immunotherapy and COVID-19 vaccines Fred Hutch has earned a reputation as one of the worlds leading cancer infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology infusion radiation proton therapy and related services and network affiliations with hospitals in five states. Together our fully integrated research and clinical care teams seek to discover new cures to the worlds deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration compassion determination excellence innovation integrity and respect. Our mission is directly tied to the humanity dignity and inherent value of each employee patient community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Mouse Development Lab (MoDeL) at Fred Hutchis dedicated to advancing mouse model development to drive groundbreaking discoveries in fundamental biology and human are seekingaShared Resources Specialist II-MoDeLresponsible for supportingand collaboratively enhancingthe preclinical researchneeds of researchersusingtransgenic and preclinical mouse modelsat Fred are expanding our team and looking for agenome engineerto help design and refine in vivo models using cutting-edge molecular and cellular biology tools. If you are passionate aboutin vivo modelingandCRISPR-based genome editing and enjoy both the molecular and hands-on aspects of mouse research we encourage you to ResourcesSpecialistII- MoDeLwillperform a variety of technical proceduresrelated topreclinical models and bench top workto support the science of creating and maintaining preclinical mouse position assumes mastery of all requirements and duties of the Specialist I.

At Fred Hutchinson Cancer Center all employees are expected todemonstratea commitment toour values of collaboration compassion determination excellence innovation integrity and respect.

Please include a cover letter describing your interest in this position.

• Research Support:Tasks include:
  
  • Perform basic molecular biology procedures such as designing and validating PCR assays and performing DNA extraction for Sanger sequencing or NGS workflows.
  • Familiarity withCRISPR techniques including design execution and validation of genome editing experiments isrequired.
  • Experience designing andvalidatingPCR assays for various applications such as genotyping cloning or expression analysis isrequired.
  • Hands-on experiencein animal care including mouse colony management breeding strategies tissue biopsies for genotyping andinjectionsthrough intravenousintraperitonealand subcutaneous routes isrequired.
  • Additionalresearch support tasksmayinclude managingsurgical mouse models.
• Research development:This position is expected to provide a high level of support for users by establishing and maintaining positive collaborative working relationships with faculty and external users. Develop advanced protocols or creative solutions and deliver high quality models with an added ability to guide users in model capable of assisting or leading in experimental design collaboratively with users.
• Equipment Oversight: Oversee supply management and preparation. Develop techniques to review and identify new equipment needs.
• Training and Education: Develop team SOPs training materials and guidelines for investigator use. May supervise work-study students interns and lab aids. Present on new or expanded technologies within MoDeL. Mentor junior staff within the MoDeL.
• Administrative tasks: Report results to users; accurately document laboratory activities; coordinate and initiate equipment maintenance visits from vendors; assist MoDeL Administrative Manager in performing billing and cost accounting; foster positive relationships with vendors and service engineers who support MoDeL.
• Regulatory and Compliance:Assure that all work done is in accordance with an IACUC approved protocol. Assist investigative staff in the creation of IACUC protocols for use in preclinical models.
• Other duties as assigned include work on weekends evenings or holiday shifts as part of a rotation.

MINIMUM QUALIFICATIONS:

• Bachelors Degree and 2 years of experience OR
• Associate Degree and 5 years of experience OR
• GED/High School Diploma and 7 years of experience.

PREFERRED QUALIFICATIONS:

• AALAS certification at the LAT or higher level is recommended and persons hired for this position should continue to pursue this certification as soon as possible once eligible until achieved
• Demonstrated ability to learn and adapt to new systems and techniques;
• Ability to learn allPCM procedural techniques;
• Strongunderstanding of preclinical research using in vivo models;
• Advancedrodent handling and procedural/ surgicalskills;
• Small animal surgeriesusingstereomicroscope;
• Understanding of molecular biology techniques and concepts;
• Experience with bioinformatics tools including but not limited to databases such as GenBankEnsembl and UCSC Genome Browser Sequence alignment tools (e.g. BLASTClustalW) andprotein
• Translation and basic sequence analysis;
• Familiarity with CRISPR techniques including design execution and validation of genome editing experiments;
• Experience in designing andvalidatingPCR assays for various applications such as genotyping cloning or expression analysis;
• Proficiency in DNA extraction techniques and experience with Sanger sequencing workflows including sample preparation and data analysis;
• Experience working in a core lab environment;
• Excellent communication and organizational skills;
• Ability to work in a collaborative team-oriented environment;
• Experience withMS Office suite of applications (Outlook Word Excel Sharepoint Teams One Driveetc);
• Record keeping and database management;
• Capable of undertaking work with minimal supervision and ability to manage multiple projects simultaneously

The hourly pay range for this position is from $31.83 to $47.73 and pay offered will be based on experience and qualifications.

This position is not eligible for H-1B sponsorship at this time.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health well-being and financial security. Benefits include medical/vision dental flexible spending accounts life disability retirement family life support employee assistance program onsite health clinic tuition reimbursement paid vacation (12-22 days per year) paid sick leave (12-25 days per year) paid holidays (13 days per year) and paid parental leave (up to 4 weeks).