This PhD position is intended for candidates with a strong interest in sensor development and multimodal signal processing who are motivated to work in a multidisciplinary environment at the interface of engineering and clinical research.
Human olfaction is critical for functions such as hazard detection food perception and personal hygiene. However olfactory disorders affect nearly 20% of the population and can substantially diminish quality of life. A key limitation of current clinical assessment methods is their strong reliance on subjective patient reporting leading to limited reliability poor reproducibility and restricted insight into the underlying physiological mechanisms.
In this project you will tackle this problem by designing and developing a novel sensing and data-driven evaluation system for olfactory function. You will engineer a sensor setup capable of topographically mapping nasal sensory responses and integrate it with controlled stimuli generated by an olfactometer. Multiple biosignals (including EEG negative mucosal potential and peak nasal inspiratory flow) will be synchronously acquired and fused using an AI-based signal processing and modeling framework. Patient-specific parameters (e.g. age sex comorbidities allergies smoking history) will be incorporated to enable personalized and objective assessment.
The developed system will be validated in a clinical study investigating the effects of endoscopic endonasal skull base surgery on olfactory function. Postoperative smell loss exhibits high inter-patient variability making it an ideal use case for advanced sensing multimodal data fusion and intelligent analysis.
A meaningful job in a dynamic and ambitious university in an interdisciplinary setting and within an international network. You will work on a beautiful green campus within walking distance of the central train addition we offer you:
Eindhoven University of Technology is a leading international university within the Brainport region where scientific curiosity meets a hands-on mindset. We work in an open and collaborative way with high-tech industries to tackle complex societal challenges. Our responsible and respectful approach ensures impact today and in the future. TU/e is home to over 13000 students and more than 7000 staff forming a diverse and vibrant academic community.
The Department of Mechanical Engineering department conducts world-class research aligned with the technological interests of the high-tech industry in the Netherlands with a focus on the Brainport region. Our goal is to produce engineers who are both scientifically educated and application-driven by providing a balanced education and research program that combines fundamental and application aspects. We equip our graduates with practical and theoretical expertise preparing them optimally for future challenges.Do you recognize yourself in this profile and would you like to know more Please contact the hiring managerJulie Legrand Assistant Professor .
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