Senior Director, Information Technology

Title: Senior Director IT

PacBio (NASDAQ: PACB) is a premier life science technology company that designs develops and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health. We are now entering the century of biology and genomics is at the heart of the next revolution. Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the PacBio team.

The Senior Director IT is responsible for leading the global IT organization at PacBio encompassing teams that support enterprise financial manufacturing and R&D information systems. This is a highly visible cross-functional leadership role that partners closely with executive leadership and stakeholders across the company to enable business strategy operational excellence and innovation through secure scalable and compliant technology solutions.

This role is ideal for an experienced IT leader with a strong background in life sciences and public-company environments deep expertise in regulated systems and a demonstrated ability to balance strategic vision with operational execution. Cybersecurity risk management compliance and management of IT operations and business applications teams are core responsibilities of this role.

Responsibilities:

• Lead develop and scale a high-performing IT organization including managers and senior technical leaders.
• Foster a culture of accountability service excellence security awareness and continuous improvement.
• Define and execute a multi-year IT strategy and technology roadmap aligned with PacBios business objectives.
• Partner closely with Finance Manufacturing R&D Quality Legal and Commercial teams to support business needs and continually improve operational efficiency.
• Own PacBios cybersecurity strategy posture and operations including prevention detection response and recovery.
• Ensure compliance with ISO 27001 SOX and other applicable regulatory and audit requirements including leading coordinating and interfacing directly with internal and external SOX auditors.
• Lead IT risk management security governance incident response planning and third-party risk management.
• Establish and maintain security policies standards and controls across infrastructure applications and data.
• Partner with internal and external auditors to support audits and remediation activities.
• Ensure IT systems supporting regulated processes comply with validation and quality requirements (e.g. GxP).
• Own IT governance frameworks including SDLC change management access controls and data governance.
• Maintain audit readiness and documentation across systems and processes. Oversee enterprise architecture application portfolio management and system lifecycle planning.
• Lead the operation and evolution of hybrid infrastructure including on-premises and cloud environments.
• Support high-performance computing (HPC) and large-scale storage platforms for R&D and data-intensive workloads.
• Drive reliability scalability and performance of mission-critical systems.
• Drive modernization initiatives including cloud adoption automation and legacy system rationalization.
• Own the IT budget forecasting and cost optimization initiatives.
• Manage strategic vendor relationships system integrators and managed service providers.

Required Qualifications:

• Bachelors degree in Information Systems Computer Science Engineering or a related field; advanced degree preferred.
• 12 years of progressive IT experience including significant leadership at the director or senior director level.
• Experience in a public company preferably within life sciences biotechnology or a regulated industry.
• Demonstrated experience with SOX compliance remediation and internal/external audits.
• Hands-on leadership experience with ISO 27001 security frameworks and certification efforts.
• Strong knowledge of system validation enterprise architecture application management and IT governance.
• Proven experience managing hybrid IT environments including cloud on-premises infrastructure HPC and storage.
• Experience with and understanding of Jira Service Desk SAP Anaplan Salesforce PLM and MES (Siemens Opcenter).
• Provide strategic oversight and guidance for PacBios SAP ERP platform ensuring alignment with business objectives compliance requirements and enterprise architecture standards.
• Excellent executive communication skills and ability to influence across functions.

Preferred Experience:

• CISSP or equivalent cybersecurity certification strongly desired.
• Experience taking mature organizations through ISO 27001 certification.
• Experience supporting manufacturing laboratory and R&D systems in regulated environments.
• Familiarity with data privacy regulations and global security standards.
• Track record of leading IT and security transformations at scale.

Candidates must have current authorization to work in the United States without the need for present or future sponsorship.

Non-Field Based Employees are required to be onsite Monday-Thursday (Friday work from home). Depending on the role some employees may be required to be 100% onsite.

You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.

All listed tasks and responsibilities are deemed as essential functions to this position; however business conditions may require reasonable accommodations for additional tasks and responsibilities.

All qualified applicants will receive consideration for employment without regard to race sex color religion national origin protected veteran status or on the basis of disability gender identity and sexual orientation.

#LI-Onsite

Salary Range:

To all Staffing and Recruiting Agencies: Our Careers Site is only for individuals seeking a job at PacBio. Staffing and recruiting agencies and individuals being represented by an agency are not authorized to use this site or to submit profiles applications or resumes and any such submissions will be considered unsolicited. PacBio does not accept unsolicited resumes or applications from agencies. Please do not forward resumes to our jobs alias PacBio employees or any other company location. PacBio is not responsible for any fees related to unsolicited resumes/applications.

All qualified applicants will receive consideration for employment without regard to race sex color religion national origin protected veteran status or on the basis of disability gender identity and sexual orientation.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying you may contact us at or for assistance.

Visit our following pages for more information on:

• FAQs

• Benefits

• Culture

• Equal Opportunity Employment