Ph.D. fellow – Cancer Immunology
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Monthly Salary:
Posted on:
19 hours ago
Vacancies:
1 Vacancy
Job Summary
About the position
A temporary position as Ph.D. fellow (doktorgradsstipend) in the Cell Signalling and Immune Regulation Group (Group Leader Prof. Kjetil Taskén) Dept. of Cancer Immunology Institute for Cancer Research (ICR) Oslo University Hospital Radiumhospitalet is available for a period of three years.
The main focus of the group is to understand tumor immune evasion mechanisms and how we can interfere to boost anti-tumor immunity. We want to define future precision immune-oncology strategies. We also work with signaling networks anchoring and localization of signaling complexes and their drug targeting. Lastly we work with cancer drug sensitivity screening to explore individual drug responsiveness and resistance patterns in patient cancer cells and for use in precision cancer medicine (PCM) in oncology and hematology. The enthusiastic research team of approx. 15 people is highly international and conducts research in close collaboration with international collaborators.
Read more about the group here: University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions and we encourage all qualified candidates regardless of background to apply!
Key information
Job description
The Ph.D. fellow will carry out a project entitled Modulating the tumor microenvironment to boost the effect of CAR-T therapy in solid tumors financed by the Regional Health Authority for South-Eastern Norway (HSØ) as part of the groups research programme to understand tumor immune evasion mechanisms. We want to test strategies to block immune evasion and explore effects on combination with cell therapy by CAR-T using established models.
Work tasks:
- Examination of the effect of CAR-T cells directed to defined antigens and where tumor immune evasion pathways have been genetically disrupted.
- Examination of the effect of pharmacological antagonists perturbing the same pathways on CAR-T function both in model systems and humanized models.
- Independent planning and execution of experiments.
Qualification requirements
We seek a structured and sociable person who can work independently and in the team. The successful candidate should have the following qualifications and skills:
- A . or M.D. degree (or similar) and expertise in immunology cancer biology molecular medicine or a similar area is a requirement. Grades must be compatible with the University of Oslo Faculty of Medicines requirements for admission to the Ph.D. programme.
- A CAREiN (FELASA-C) licence for animal experimentation is necessary and prior experience with animal work a benefit.
- Competence and experience with T cell immunology flow cytometry and T cell immune function assays and or cell therapy strategies would be a benefit.
- Molecular biology and biochemistry experience would be a benefit.
- Candidates with good ability to communicate in English both orally and writing will be preferred.
- Personal suitability will be considered.
Personal skills
We offer
- A dynamic and stimulating scientific environment in a young enthusiastic and motivated team of immunologists biologists and MDs. The Institute of Cancer
- Research is at the international forefront and houses top modern (2009) and excellent lab facilities with a wide range of core facilities (animal light and electron microscopy flow cytometry genomics and bioinformatics MR drug screening mass spec etc) locally or at the Rikshospitalet and UiO sites.
- Salary for PhDs. starting at 572 000 NoK per year.
- Attractive welfare benefits and a generous pension agreement in addition to Oslos family-friendly environment with its rich opportunities for culture and outdoor activities.
How to apply:
The application must include
- Cover letter with statement of motivation and research interests
- CV (summarizing education positions and academic work)
- Copies of educational certificates (academic transcripts only)
- List of reference persons: 2-3 references (name relation to candidate e-mail and phone number)
The application with attachments must be delivered in our electronic recruiting system please follow the link: Apply for this job. Foreign applicants are advised to attach an explanation of their Universitys grading system. Please note that all documents should be in English
When evaluating the application emphasis will be given to the applicants academic and personal prerequisites to carry out the project. Applicants may be called in for an interview.
Address: Oslo universitetssykehus HF Radiumhospitalet Ullernchausseen 70 0379 Oslo Norway
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- Teaching
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About Company
Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of na ... View more
