Pharmacometrics Lead Mechanistic Modeling (UK)

Make your mark for patients

We are looking for a Pharmacometrics Lead who is innovative and agile to join us in our Quantitative Clinical Pharmacology group based at our research site inSlough (UK) or Braine (Belgium).

About the role

You will be leading and delivering the Pharmacometrics strategy to support development of our assets extrapolation (where appropriate) dose selection trial design PIP development and ongoing evaluation of data as generated.

Who youll work with

Reporting to the Global Head of Pharmacometrics.

What youll do

• Performing hands-on PBPK QSP and clinical trial simulations on an assigned project.
• Transform PBPK and QSP analyses into actionable insights and communicate these findings effectively to project teams and stakeholders.
• Developing submission ready fit for purpose Pharmacometrics analysis plans and reports.
• Initiating and overseeing outsourced pharmacometrics activities and further internalizing the work as needed.
• Supporting the development of a team from both a technical and scientific perspective to ensure state-of-the-art mechanistic approaches are applied to optimize drug discovery and development.
• Having a working knowledge about regulatory pathways on a global basis and opportunities for collaboration with health authorities (either through working parties advice meetings and other initiatives) in pediatrics Neurology and Immunology.
• Working closely with the QCP leads assigned to the various projects to ensure clear integration of the pharmacometrics aspects into the programs.
• Work with IT to ensure appropriate system validation and integration with other software is enabled.
• Promoting MID3 internally and externally.

Interested For this role youll need the following education experience and skills

• Doctorate (PhD or MD) in related disciplines of Pharmaceutical Sciences Statistics or Engineering with at least 6 years in PBPK and QSP modeling in (Bio)pharmaceutical industry.
• Hands on expertise in PK-Sim /MoBi SimCyp GastroPlus MatLab and R. Hands on experience with NONMEM and python is an additional advantage.
• Hands-on experience in population PK/PD modeling is desirable.
• Agile mindset with a proven ability to adjust by prioritizing multiple tasks.
• Outstanding communication organizational and presentation skills.

Are you ready to go beyond to create value and make your mark for patients If this sounds like you then we would love to hear from you!

About us
UCB is a global biopharmaceutical company focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe inspired by patients and driven by science.

Why work with us
At UCB we dont just complete tasks we create value. We arent afraid to push forward collaborate and innovate to make our mark for patients. We have a caring supportive culture where everyone feels included respected and has equal opportunities to do their best work. We go beyond to create value for our patients and always with a human focus whether thats on our patients our employees or our planet. Working for us you will discover a place where you can grow and have the freedom to carve your own career path to achieve your full potential.

At UCB weve embraced a hybrid-first approach to work bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.