Enterprise Architect (Staff)
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Job Location:
Palo Alto, CA - USA
Monthly Salary:
$ 153600 - 211300
Posted on:
2 days ago
Vacancies:
1 Vacancy
Job Summary
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012 Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care including screening to find cancer early monitoring for recurrence in early-stage cancer and treatment selection for patients with advanced cancer. For more information visitand follow the company onLinkedInX (Twitter)andFacebook.
About the Role
We are seeking a strategic and hands-on Enterprise Architect to design and evolve Guardants technology ecosystem as we scale 5x over the next two years. This role is enterprise-wide with authority to establish architectural standards guide platform development and accelerate delivery of reusable services and components across the business.
The Enterprise Architect will partner with engineers product security data science and clinical operations teams to ensure our systems are scalable secure compliant and patient-impact driven.
Key Responsibilities
Strategic Enterprise Architecture
Define and govern Guardants enterprise architecture aligning technology capabilities with business priorities and oncology innovation goals.Reusable Platforms & Components
Design shared platforms modular services and reusable components that enable faster delivery reduce duplication and improve scalability.Scale & Performance
Architect cloud-based systems to handle 5x growth in lab throughput data analytics and digital engagement within 24 months.Data & Analytics Enablement
Define enterprise data strategies and platforms for governance interoperability real-time analytics and AI/ML pipelines.Cloud Transformation
Drive an cloud-first architecture (AWS) ensuring resilience elasticity security and cost efficiency at scale.Security & Privacy by Design
Embed security and privacy controls into every platform ensuring compliance with HIPAA GDPR CLIA CAP and FDA (21 CFR Part 11).Governance & Standards
Establish reference architectures patterns and frameworks to reduce technical debt improve adoption and enforce consistency across engineering teams.Innovation & Emerging Tech
Evaluate and introduce new technologies (e.g. automation event-driven architectures AI/ML accelerators) that strengthen Guardants competitive edge.Influence & Mentorship
Act as a trusted advisor to the engineering leaders while mentoring architects and engineers across the company.
Qualifications
10 years of progressive experience in software engineering and architecture with 5 years in enterprise/solution architecture leadership.
Bachelors degree in Computer Science Management Information Systems Software Engineering Electrical Engineering Computer Engineering Information Systems Bioinformatics or a related technical field required.
Proven ability to design and scale digital and enterprise platforms in cloud (AWS) environments.
Strong expertise in modular architectures reusable platforms and component-driven design.
Experience with lab informatics clinical systems or healthcare data platforms strongly preferred.
Deep knowledge of security compliance and healthcare interoperability standards (e.g. HL7 FHIR LOINC).
Familiarity with authorization policy frameworks and applying them to flexibly protect assets and resources.
Exceptional communication and leadership skills with ability to influence executives engineers and clinical stakeholders.
Preferred Qualifications
Experience designing reusable platforms in diagnostics biotech or healthcare technology companies.
Track record of building enterprise-wide architectures that accelerated delivery while reducing integration complexity.
Success Metrics
Delivered AWS-based architectures supporting 5x scale in lab throughput analytics and digital services.
Established reusable platforms/components that shortened development cycles and improved efficiency.
Reduced technical debt and system fragmentation while enabling faster feature and product launches.
Implemented governance frameworks that improved security compliance and platform adoption across teams.
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Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays Tuesdays and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
Employee may be required to lift routine office supplies and use office of the work is performed in a desk/office environment; however there may be exposure to high noise levels fumes and biohazard material in the laboratory to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities long-term conditions mental health conditions or sincerely held religious beliefs. If you need support please reach out to
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health Inc. and how it is used please review ourPrivacy Notice for Job Applicants.
Please visit our career page at: Experience:
Staff IC
Key Skills
- SAP BusinessObjects
- Enterprise Architecture
- Hybris
- SAP HANA
- SAP
- TOGAF
- Solution Architecture
- Cloud Architecture
- SAP BW 4HANA
- Salesforce
- SAP S/4HANA
- SAP ERP
About Company
Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient cl ... View more
