Principal Scientist, Biological Research

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

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About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Principal Scientist Biological Research to be in La Jolla CA.

Purpose:
We are seeking a highly motivated and innovative scientist to lead the development and implementation of advanced immunological cell-based assays to support drug discovery programs. The successful candidate will be able to lead early drug discovery screening efforts with a proven ability to apply cutting-edge technologies in a dynamic and collaborative environment to advance J&Js Immunology discovery position is within Mechanistic Cellular Pharmacology team.

You will be responsible for:

• Design develop and optimize complex cell-based assays utilizing suitable immune cell types to support discovery projects from hit identification through lead optimization.
• Drive technology innovation for HT disease-relevant screening platforms in collaboration with automation team.
• Lead Immunology discovery programs by leveraging broad technology platforms of DTMP (Discovery Technology and Molecular Pharmacology).
• Develop compelling scientific presentations and reports for internal reviews and external publications.
• Provide scientific leadership and mentorship to team members; Foster collaborative relationships with stakeholders.
• Build and maintain effective scientific networks across internal and external stakeholders.
• Ensure compliance with industry standards and best practices in assay development and data integrity.

Qualifications / Requirements:

Education:

• Bachelors degree is required
• Ph.D. in Pharmacology Immunology or related fields is highly preferred
  

Required:

• Minimum 6 years of experience in the pharmaceutical industry and/or academic setting
• Minimum 3 years of pharmaceutical industry experience in assay design and HTS specialization
• Hands-on flow cytometry and imaging experience
• Strong knowledge of immuno-cell biology pharmacology and in vitro/in vivo pharmacology models.
• Excellent problem-solving skills open collaborative style and ability to thrive in a fast-paced competitive environment.
• Outstanding communication skills to convey scientific credibility and influence decision-making.
• Ability to lead cross-functional teams and manage multiple priorities effectively.
• Positive attitude and strong interpersonal skills for stakeholder engagement.

Preferred:

• Demonstrated ability to apply big data analytics and computational tools in drug discovery.
• Track record of strategic thinking and execution in assay development and technology innovation.
  

The anticipated base pay range for this position in the US is $117000 to $201250.

The Company maintains highly competitive performance-based compensation programs. Under current guidelines this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporations performance over a calendar/ performance year. Bonuses are awarded at the Companys discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance.

Employees may be eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:

• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay including Floating Holidays - up to 13 days per calendar year
• Work Personal and Family Time - up to 40 hours per calendar year

For additional general information on company benefits please go to: job posting is anticipated to close on January 1 2026. The Company may however extend this time-period in which case the posting will remain available on to accept additional applications.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

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