Protein Design Scientist
Share
Job Location:
Durham, NC - USA
Monthly Salary:
Not Disclosed
Posted on:
5 hours ago
Vacancies:
1 Vacancy
Job Summary
At Syngenta we believe every employee has a role to play in safely feeding the world and taking care of our planet. To support that challenge the Bioinformatics Group is seeking a Protein Design Scientist located in Durham North Carolina. As a Protein Design Scientist you will be an important link in a high-performance team of trait design scientists. You will bring cutting-edge skills in protein modeling structure prediction and AI-driven design approaches to provide innovative solutions for enhancing trait performance.
Accountabilities:
- Lead the advancement of functional capabilities in protein design by integrating sequence and structure modeling to optimize specific agricultural traits.
- Join cross-functional research teams to deliver next-generation leads to the trait product pipeline.
- Become an active member of the Bioinformatics Group and drive innovation in protein design and sequence modeling.
- Synthesize results and clearly communicate progress and challenges to a range of stakeholders.
- Implement and leverage AI/ML approaches including large language models to accelerate protein design workflows.
- Create and leverage protein structure and sequence data to support discovery research efforts in insect control herbicide tolerance disease control and genome editing.
- Develop and apply AI-driven approaches including large language models and embedding techniques to predict structure stability and activity directly from sequence data.
- Be an active member of a scientific group that leverages research in protein structure and function deep learning and artificial intelligence genomics proteomics and molecular biology to address trait gene discovery in agricultural biotechnology.
- Monitor and implement advancements in sequence- and structure-based protein design and informatics to support discovery research objectives.
- Liaise with external research groups and provide technical expertise in research collaborations.
Qualifications :
PLEASE NOTE -- Candidates must be already located in the United States and not require visa sponsorship now or in the future (includes OPT).
Required:
- PhD with 1 years of experience in bioinformatics computational biology biochemistry biophysics or a related field.
- Strong understanding of protein biochemistry or biophysics related to protein structure/function.
- Demonstrated track record in protein engineering and expertise in computational sequence analysis.
- Working knowledge of AI/ML applications in protein design including experience with large language models embedding techniques and generative sequence models.
- Excellent communication skills and the ability to work in a highly dynamic and collaborative environment.
Desired:
- Expertise using protein modeling and structural analysis software applications (ProGen ESM family models ProteinMPNN AlphaFold2/3 RFdiffusion Rosetta etc.).
- Experience applying generative AI and sequence models to protein design challenges.
- Proficiency with methods and tools to query and analyze large datasets of public and proprietary sequence and structural data.
- Experience working in cloud computing environments and containerized workflows.
- Familiarity with modern ML frameworks (PyTorch TensorFlow JAX).
- Experience in trait or agriculture domains.
Additional Information :
What We Offer:
- A culture that celebrates diversity & inclusion promotes professional development and strives for a work-life balance that supports the team members. Offers flexible work options to support your work and personal needs.
- Full Benefit Package (Medical Dental & Vision) that starts your first day.
- 401k plan with company match Profit Sharing & Retirement Savings Contribution.
- Paid Vacation Paid Holidays Maternity and Paternity Leave Education Assistance Wellness Programs Corporate Discounts among other benefits.
Syngenta has been ranked as a top employer by Science Journal. Learn more about our team and our mission here: is an Equal Opportunity Employer and does not discriminate in recruitment hiring training promotion or any other employment practices for reasons of race color religion gender national origin age sexual orientation marital or veteran status disability or any other legally protected status.
WL: 4A
#LI-Hybrid
Remote Work :
No
Employment Type :
Full-time
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
About Company
To help feed 10 billion people while reducing emissions and improve biodiversity. This is our mission as the global agriculture technology leader. With 59,000 employees in more than 100 countries and hundreds of thousands of agricultural partners worldwide, we are committed to transfo ... View more
