Lyophilisation Technician – Sterile Manufacturing
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Job Location:
Monthly Salary:
Posted on:
30+ days ago
Vacancies:
1 Vacancy
Job Summary
Work Schedule
OtherEnvironmental Conditions
Cleanroom: no hair products jewelry makeup nail polish perfume exposed piercings facial hair etc... allowedJob Description
When you join Thermo Fisher Scientific at our Swindon site you become part of one of the UKs leading sterile manufacturing hubsan environment driven by precision innovation and operational excellence. Our site plays a key role in delivering life-changing medicines to patients worldwide. As part of a fast-growing global organization you will be supported with the tools training and development opportunities needed to perform at your best and grow your career.
Key Responsibilities
Freeze-Drying Operations
Execute freeze-drying cycles according to the production plan.
Monitor all freeze-drying cycle parameters to ensure optimal and compliant operating conditions.
Operate freeze driers for both routine production and test cycles.
Perform visual checks and review graphical data to confirm correct system performance.
GMP Documentation & Compliance
Complete all GMP documentation accurately and in a timely manner.
Report abnormal trends alarms or deviations via SCADA data and follow defined escalation pathways.
Prepare and compile freeze-drying cycle records for inclusion in batch manufacturing documentation.
Initiate deviation reports and support investigations into unexpected variations.
Process & Equipment Support
Assist in optimizing lyophilization processes to improve efficiency and reliability.
Monitor key utilities (pressure levels flow) to ensure uninterrupted operations.
Load consumables and maintain required inventory for freeze-drying support systems.
Perform basic equipment interventions (e.g. clamp adjustments nitrogen filter changes leak checks).
Report utility or equipment alarms promptly to enable rapid maintenance response.
Environmental Monitoring
Monitor environmental conditions in cleanrooms and support areas via FMS.
Identify abnormal trends and ensure appropriate escalation according to SOPs.
Compile routine environmental monitoring printouts for QA review and approval.
Additional Production Activities
Support other production-related operations during low lyophilization activity periods.
Health & Safety
Follow all emergency procedures and safe systems of work.
Adhere to EH&S requirements and maintain strong safety behavior.
Experience & Qualifications
ONC in Electrical Mechanical Electronic Engineering or Instrumentation.
Experience in a pharmaceutical environment ideally with freeze-dryer operations.
Strong understanding of cGMP.
Proficiency with SCADA systems and computerized process monitoring.
Experience operating equipment with multiple cycles and complex functionality.
Key Attributes
Detail-oriented methodical and highly disciplined.
Strong judgment based on SOPs validated parameters and experience.
Ability to work independently within a 24/7 shift pattern and take accountability for repetitive critical operations.
Clear written and verbal communication skills.
Willingness to seek cross-functional support when needed to maintain process reliability.
Ready to make an impact Apply now.
Required Experience:
IC
Key Skills
- Lean Manufacturing
- Hand Tools
- Basic Math
- Math
- Mechanical Knowledge
- Assembly Experience
- Computer Literacy
- Schematics
- cGMP
- Clamp Truck
- Programmable Logic Controllers
- Manufacturing
About Company
Electron microscopes reveal hidden wonders that are smaller than the human eye can see. They fire electrons and create images, magnifying micrometer and nanometer structures by up to ten million times, providing a spectacular level of detail, even allowing researchers to view single a ... View more
