Sr. Principal Scientist, Amazon Health Science & Analytics
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Job Location:
Santa Clara County, CA - USA
Yearly Salary:
$ 240100 - 350000
Posted on:
7 hours ago
Vacancies:
1 Vacancy
Job Summary
We are looking for a senior AI/ML researcher who can architect and guide a long-horizon ML strategy for a healthcare-focused organization building a durable domain-specific healthcare foundation model and a high-reliability inference system. This person will define the technical vision for how our organization should leverage frontier models when and how to build proprietary domain models and how to sequence capability development into monetizable customer-facing features while working high quality safety and regulatory constraints expected within healthcare. This individual will serve as a senior technical advisor on frontier-model integration data strategy evaluation and safety architecture. They will partner closely across product engineering clinical and compliance teams to ensure that the AI system is safe reliable economically viable and capable of compounding differentiation over time.
The ideal candidate brings deep hands-on experience training or adapting large-scale models (LLMs multimodal or MoE systems) with strong grounding in distributed training RLHF/DPO retrieval and knowledge integration evaluation harness design and ML systems engineering.
Demonstrated experience shipping ML capabilities in high-stakes or regulated domainshealthcare autonomy finance or large enterprise platformsis highly valuable as is familiarity with clinical data workflow constraints or ISO-aligned or internationally acknowledged safety practices and standards. This hire must combine research depth pragmatic product sense and systems leadership to build a capability that endures for many years.
- MS/PhD in computer vision machine learning computer science or related quantitative and computationally intensive disciplines.
- Proven track record in shipping large scale AI/ML products.
- 10 years working in related AI domains.
- 5 Language/multimodal model tuning and optimization experience.
- 5 years of advising engineering and science teams.
- Experience in healthcare pharmaceuticals biotechnology etc.
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status disability or other legally protected status.
Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees supervisors and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees supervisors and staff to ensure exceptional customer service; and follow all federal state and local laws and Company policies. Criminal history may have a direct adverse and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above as well as the abilities to adhere to company policies exercise sound judgment effectively manage stress and work safely and respectfully with others exhibit trustworthiness and professionalism and safeguard business operations and the Companys reputation. Pursuant to the Los Angeles County Fair Chance Ordinance we will consider for employment qualified applicants with arrest and conviction records.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process including support for the interview or onboarding process please visit for more information. If the country/region youre applying in isnt listed please contact your Recruiting Partner.
Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $240100/year in our lowest geographic market up to $350000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge skills and experience. Amazon is a total compensation company. Dependent on the position offered equity sign-on payments and other forms of compensation may be provided as part of a total compensation package in addition to a full range of medical financial and/or other benefits. For more information please visit This position will remain posted until filled. Applicants should apply via our internal or external career site.
The ideal candidate brings deep hands-on experience training or adapting large-scale models (LLMs multimodal or MoE systems) with strong grounding in distributed training RLHF/DPO retrieval and knowledge integration evaluation harness design and ML systems engineering.
Demonstrated experience shipping ML capabilities in high-stakes or regulated domainshealthcare autonomy finance or large enterprise platformsis highly valuable as is familiarity with clinical data workflow constraints or ISO-aligned or internationally acknowledged safety practices and standards. This hire must combine research depth pragmatic product sense and systems leadership to build a capability that endures for many years.
- MS/PhD in computer vision machine learning computer science or related quantitative and computationally intensive disciplines.
- Proven track record in shipping large scale AI/ML products.
- 10 years working in related AI domains.
- 5 Language/multimodal model tuning and optimization experience.
- 5 years of advising engineering and science teams.
- Experience in healthcare pharmaceuticals biotechnology etc.
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status disability or other legally protected status.
Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees supervisors and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees supervisors and staff to ensure exceptional customer service; and follow all federal state and local laws and Company policies. Criminal history may have a direct adverse and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above as well as the abilities to adhere to company policies exercise sound judgment effectively manage stress and work safely and respectfully with others exhibit trustworthiness and professionalism and safeguard business operations and the Companys reputation. Pursuant to the Los Angeles County Fair Chance Ordinance we will consider for employment qualified applicants with arrest and conviction records.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process including support for the interview or onboarding process please visit for more information. If the country/region youre applying in isnt listed please contact your Recruiting Partner.
Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $240100/year in our lowest geographic market up to $350000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge skills and experience. Amazon is a total compensation company. Dependent on the position offered equity sign-on payments and other forms of compensation may be provided as part of a total compensation package in addition to a full range of medical financial and/or other benefits. For more information please visit This position will remain posted until filled. Applicants should apply via our internal or external career site.
Required Experience:
Staff IC
Key Skills
- Machine Learning
- Python
- Data Science
- AI
- R
- Research Experience
- Sensors
- Drug Discovery
- Research & Development
- Natural Language Processing
- Data Analysis Skills
- Toxicology Experience
About Company
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