Postdoctoral Scientist (Computational & Structural Bioinformatics)
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Job Location:
Foster, CA - USA
Monthly Salary:
$ 126820 - 164120
Posted on:
6 hours ago
Vacancies:
1 Vacancy
Job Summary
At Gilead were creating a healthier world for all people. For more than 35 years weve tackled diseases such as HIV viral hepatitis COVID-19 and cancer working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the worlds biggest health challenges and our mission requires collaboration determination and a relentless drive to make a difference.
Every member of Gileads team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions and were looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future you are the key driver in evolving our culture and creating an environment where every employee feels included developed and empowered to fulfil their aspirations. Join Gilead and help create possible together.
Job Description
Location: Foster City CA
Term: 3-Year Fixed Term
About the Role
Join a pioneering team at the forefront of computational and structural biology driving innovation to transform therapeutic discovery. We are seeking an exceptional Postdoctoral Scientist to lead research focused on predicting and optimizing proteinprotein interactions using cutting-edge approaches that combine physics-based modeling machine learning and experimental validation advancing the design of next-generation proteins and antibodies.
This position is a joint appointment between Research Data Sciences and Protein Therapeutics providing a unique opportunity for cross-functional collaboration and exposure to diverse expertise.
As a Postdoctoral Scientist you will have the freedom to design and lead an independent research project publish in high-impact journals and work alongside world-class scientists across computational and experimental disciplines. Your contributions will directly shape the future of biologics and antibody therapeutics.
What Youll Do
Develop advanced computational workflows for protein modeling structural analysis and molecular simulations.
Apply machine learning and physics-based approaches to predict and optimize protein-protein interactions.
Analyze large-scale biological datasets to uncover insights that guide experimental design.
Validate computational predictions and generate critical training datasets in the lab.
Optimize automated cloud-based pipelines for large-scale predictions and data processing.
Publish and present your findings at top-tier conferences and journals.
Basic Qualifications
Ph.D. in Computational Biology Bioinformatics Structural Biology Biophysics or related fields.
At least one first-author publication in a peer-reviewed journal.
Strong Python programming skills with extensive experience using scientific libraries (e.g. NumPy SciPy pandas) and deep learning frameworks including PyTorch and TensorFlow.
Expertise in protein modeling tools (AlphaFold RFDiffusion Rosetta PyMOL etc)
Hands-on experience with molecular dynamics packages (AMBER GROMACS etc) is a plus.
Familiarity with antibody structure and protein engineering principles.
Proficiency in Linux environments and deploying workflows on HPC clusters.
Excellent problem-solving and communication skills.
Preferred Qualifications (one or more of the following)
Experience with graph neural networks diffusion models or generative frameworks for antibody design and optimization.
Knowledge of enhanced sampling techniques (Metadynamics Umbrella sampling).
Understanding binding thermodynamics and free energy calculations.
Experience and/or familiarity with approaches for affinity validation and screening in the lab (e.g. high throughput recombinant protein production ELISA SPR/BLI flow cytometry display technologies NGS) - training provided as needed.
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Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment and is dedicated to fostering an inclusive work environment comprised of diverse perspectives backgrounds and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race color religion national origin sex age sexual orientation physical or mental disabilitygenetic information or characteristic gender identity and expression veteran status or other non-job related characteristics or other prohibited grounds specified in applicable federal state and local order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Era Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact for assistance.
For more information about equal employment opportunity protections please view theKnow Your Rights poster.
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Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about discussed or disclosed their own pay or the pay of another employee or applicant. However employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information unless the disclosure is (a) in response to a formal complaint or charge (b) in furtherance of an investigation proceeding hearing or action including an investigation conducted by the employer (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.
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Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday.
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
About Company
Gilead Sciences is continuing to hire for all open roles. Our interview process may be conducted virtually and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensu ... View more
